Browsing Chemical Engineering (CE) by Subject "Cytolysin A"
Now showing items 1-3 of 3
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Molecular Analysis of the Pore Forming Mechanism of an α-Helical Cytolysin
Pore forming toxins (PFTs) are lytic membrane binding proteins that are ubiquitous across the animal kingdom and disrupt the structural integrity of the host cell membrane. A unique characteristic of these toxins is that ... -
Molecular Dynamics simulations reveal the role of membrane cholesterol in the pore forming pathway of Cytolysin A
We investigate the interactions of pore-forming toxins (PFTs) with cholesterol-rich membranes through atomistic molecular dynamics simulations. The PFT of interest is Cytolysin A (ClyA or HlyE). Cytolysin A (ClyA), an ... -
Pore Forming Toxins : Unravelling Oligomerization Pathways and Related Kinetics
Pore forming toxins are a class of proteins secreted from a wide variety of pathogens. These toxins are implicated in several diseases such as cholera, anthrax, tuberculosis and food poisoning. The toxin proteins are ...