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dc.contributor.advisorRangarajan, P N
dc.contributor.authorSahu, Umakant
dc.date.accessioned2018-03-01T16:16:37Z
dc.date.accessioned2018-07-30T14:13:53Z
dc.date.available2018-03-01T16:16:37Z
dc.date.available2018-07-30T14:13:53Z
dc.date.issued2018-03-01
dc.date.submitted2016
dc.identifier.urihttps://etd.iisc.ac.in/handle/2005/3212
dc.identifier.abstracthttp://etd.iisc.ac.in/static/etd/abstracts/4075/G28356-Abs.pdfen_US
dc.description.abstractThe present study is aimed at examining the ability of Pichia pastoris to utilize acetate and amino acids as the sole sources of carbon. We demonstrate that the zinc finger transcription factor Mxr1p, which is a positive regulator of methanol metabolism, is also required for the growth of P. pastoris in media containing acetate or amino acids as the sole source of carbon. We have identified the target genes of Mxr1p in cells cultured in media containing acetate or amino acids as the sole carbon source. We conclude that Mxr1p is a global regulator of multiple metabolic pathways in P. pastoris.en_US
dc.language.isoen_USen_US
dc.relation.ispartofseriesG28356en_US
dc.subjectMethanol Expression Regulator 1en_US
dc.subjectMethylotrophic Yeast Pichia pastorisen_US
dc.subjectMxr1pen_US
dc.subjectMethanol Utilization Pathwayen_US
dc.subjectPichia pastorisen_US
dc.subjectP. pastorisen_US
dc.subjectZinc Finger Transcription Factoren_US
dc.subjectMultiple Metabolic Pathwaysen_US
dc.subject.classificationBiochemistryen_US
dc.titleMxr1p is a Global Regulator of Multiple Metabolic Pathways in the Methylotrophic Yeast Pichia Pastorisen_US
dc.typeThesisen_US
dc.degree.namePhDen_US
dc.degree.levelDoctoralen_US
dc.degree.disciplineFaculty of Scienceen_US


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