Manipulating and utilizing fluid flows at microscale provides several opportunities towards technological advancement in different domains such as (but not limited to) lab-on-chip devices for mimicking biological laboratory ...

This thesis explores the development and application of microsystems to advance our understanding of disease biology. The overarching goal is to enhance diagnostic and therapeutic strategies through precise and physiologically ...

Cancer cells are shed from metastatic primary tumors, bearing the potential for blood-borne metastasis to distant vital organs. Metastasis is predominantly responsible for cancer-related deaths. These circulating tumor ...

The peritoneal cavity of a patient suffering from advanced epithelial ovarian cancer is filled with disseminated multicellular aggregates, commonly known as spheroids. These spheroids colonize abdominal organs leading to ...

Single-cell analysis is extremely important for discovering unique characteristics of individual cells, identifying cell populations of interest, and understanding their behaviour during disease conditions. With the advent ...

Organ-on-chip devices are advanced engineered microfluidic systems that replicate human organ functions on a small scale. They utilize living cells from human tissues and combine them with biomaterials to create a dynamic ...