This thesis explores the development and application of microsystems to advance our understanding of disease biology. The overarching goal is to enhance diagnostic and therapeutic strategies through precise and physiologically ...

Cancer cells are shed from metastatic primary tumors, bearing the potential for blood-borne metastasis to distant vital organs. Metastasis is predominantly responsible for cancer-related deaths. These circulating tumor ...

The peritoneal cavity of a patient suffering from advanced epithelial ovarian cancer is filled with disseminated multicellular aggregates, commonly known as spheroids. These spheroids colonize abdominal organs leading to ...