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Engineering 3D Organotypic Models for the Study of Breast Cancer Metastasis
Breast cancer is the most common form of cancer among women the world over.
Metastasis, or, the spreading of the primary tumor to other vital organs, is the major
cause of mortality in breast cancer. Metastasis is a ...
Dynamical systems biology approach to identify mediators of the Epithelial-Hybrid-Mesenchymal spectrum
Cancer metastasis – the spread of cancer cells from one organ to another – remains the major cause of cancer-related deaths. A hallmark of metastasizing cells is their ability to adapt quickly and reversibly to their dynamic ...
Design Principles of Phenotypic Robustness and Plasticity in Gene Regulatory Networks underlying Cancer Metastasis
Metastasis – the process of cancer cells leaving the primary tumor and colonizing multiple organs – remains a major cause of cancer mortality. However, it is a highly inefficient process with only 0.01% of disseminated ...