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Biophysics of focal adhesion and cytoskeletal remodeling under fluid shear
Mechanosensors play a vital role in how cells respond to external forces, impacting cell-substrate adhesions through integrin clustering and focal adhesion formation associated with actomyosin contractility. Adhesions ...
Bacterial cellular heterogeneity in inducible gene expression and drug susceptibility
Biological processes are inherently noisy, and such stochasticity can result in significant
cell to cell variability in isogenic bacterial populations. Functionally, cellular
heterogeneity can have significant impact on ...
Integrating Computational Tools and Models to Study Positive-sense RNA Virus Lifecycle
Positive-sense single-stranded RNA ((+)RNA) viruses pose significant challenges to public health. Notable families such as Enteroviridae, Flaviviridae, and Coronaviridae have caused epidemics (Dengue, Poliomyelitis, Zika) ...