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A Control Systems Approach to Understanding Saccadic Eye Movements
The oculomotor system is extensively studied using concepts of control theory like optimal control, feedback control, and predictive control. But these studies have largely been restricted to investigating the central ...
The Role of Basal Ganglia and Redundancy in Supervised Motor Learning
Human sensorimotor control can achieve highly reliable movements under circumstances of noise, redundancy, uncertainty, and sensory delays. Our ability to achieve reliable and accurate movements is in the fact we have a ...
Raman Microspectroscopic Studies on Differentiating Bacteria, Detecting Antimicrobial Resistance and Delineating Biomarkers of Sepsis
Over the last few decades, the development of several new techniques as well as sophisticated instruments have contributed to a better understanding of biological systems. Among these, Raman spectroscopy has emerged as an ...
Engineering Disease Models for Cardiac and Skeletal Muscle Tissues
Biomedical research aims to gain deeper insights into the mechanisms of human pathophysiology to develop improved therapies and diagnostics. Despite significant advances made in the understanding and treatment of human ...
Compositionality of letter shape in word recognition
As you read this sentence, your brain just performed a miraculous task of converting collections of letter shapes into meaning. Reading is a cultural invention that is thought to exploit the intrinsic recognition abilities ...
Caenorhabditis elegans-Bacteria interactions: Neuronal Regulation of Innate Immune Responses
The survival of an organism depends on its ability to sense threats and execute appropriate defense mechanisms. C. elegans is a soil-dwelling nematode that feeds on bacteria in rotting vegetation. The nematode has few ...
Engineering Graphene Oxide Surface Chemistry and Investigating Its Effect on The Physicochemical and Biological Properties
In the current study, systematic tuning of oxidation degree of GO has been explored and a two-step methodology for engineering GO surface chemistry was successfully developed. The investigation of the effects of oxidation ...
Intra- and inter-cellular drivers of Epithelial-Mesenchymal heterogeneity in cancer cells
Phenotypic heterogeneity is a fundamental feature reported across prokaryotic and eukaryotic cells. This heterogeneity enables an isogenic cell population to be composed of distinct subpopulations with varying functional ...
Bioengineering strategies to model and modulate immune cells
Optimal activation of immune cells is necessary to elicit a protective response against pathogens and foreign objects. In dysregulated immune systems, cells are aberrantly activated or exhausted. Understanding biochemical ...
Bipartite pore-forming toxin YaxAB: understanding pore formation using live-cell imaging
Bacteria employ a variety of strategies to invade and colonise the host tissue, including the secretion of toxins to overcome the cellular barrier. Bacterial pore-forming toxins (PFTs) disrupt the lipid bilayer by forming ...

