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Now showing items 11-17 of 17
Functional regulation of cytoplasmic dynein in vivo
In the crowded confines of the eukaryotic cell, where large cargo (> 100 nm) are diffusionaly constrained, intracellular transport by motor proteins plays a crucial role in the exchange of material between various compartments ...
Raman Microspectroscopic Studies on Differentiating Bacteria, Detecting Antimicrobial Resistance and Delineating Biomarkers of Sepsis
Over the last few decades, the development of several new techniques as well as sophisticated instruments have contributed to a better understanding of biological systems. Among these, Raman spectroscopy has emerged as an ...
Engineering Disease Models for Cardiac and Skeletal Muscle Tissues
Biomedical research aims to gain deeper insights into the mechanisms of human pathophysiology to develop improved therapies and diagnostics. Despite significant advances made in the understanding and treatment of human ...
Compositionality of letter shape in word recognition
As you read this sentence, your brain just performed a miraculous task of converting collections of letter shapes into meaning. Reading is a cultural invention that is thought to exploit the intrinsic recognition abilities ...
Bioengineering strategies to model and modulate immune cells
Optimal activation of immune cells is necessary to elicit a protective response against pathogens and foreign objects. In dysregulated immune systems, cells are aberrantly activated or exhausted. Understanding biochemical ...
Bipartite pore-forming toxin YaxAB: understanding pore formation using live-cell imaging
Bacteria employ a variety of strategies to invade and colonise the host tissue, including the secretion of toxins to overcome the cellular barrier. Bacterial pore-forming toxins (PFTs) disrupt the lipid bilayer by forming ...
Mechanobiology of Liver Fibrosis: Role of Hepatocytes in Fibrosis Progression
Liver fibrosis is characterized by liver scarring which disrupts the liver architecture and
impairs hepatic function. Current diagnostic tools reveal that the stiffness of the liver tissue
increases as one advances through ...

