Browsing Department of Bioengineering (BE, Earlier known as BSSE) by Subject "Research Subject Categories::NATURAL SCIENCES"
Now showing items 1-5 of 5
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Bioengineering strategies to model and modulate immune cells
Optimal activation of immune cells is necessary to elicit a protective response against pathogens and foreign objects. In dysregulated immune systems, cells are aberrantly activated or exhausted. Understanding biochemical ... -
Caenorhabditis elegans-Bacteria interactions: Neuronal Regulation of Innate Immune Responses
The survival of an organism depends on its ability to sense threats and execute appropriate defense mechanisms. C. elegans is a soil-dwelling nematode that feeds on bacteria in rotting vegetation. The nematode has few ... -
Design Principles of Phenotypic Robustness and Plasticity in Gene Regulatory Networks underlying Cancer Metastasis
Metastasis – the process of cancer cells leaving the primary tumor and colonizing multiple organs – remains a major cause of cancer mortality. However, it is a highly inefficient process with only 0.01% of disseminated ... -
Functional regulation of cytoplasmic dynein in vivo
In the crowded confines of the eukaryotic cell, where large cargo (> 100 nm) are diffusionaly constrained, intracellular transport by motor proteins plays a crucial role in the exchange of material between various compartments ... -
Multistability in cellular differentiation enabled by three and four node mutually repressive regulatory networks: A case study of CD4+ T-cell decision making
Cellular differentiation is controlled by the complex dynamics of gene regulatory networks (GRNs), often featuring multistability, where multiple stable states represent different phenotypes. A common example is the toggle ...