Browsing Department of Bioengineering (BE, Earlier known as BSSE) by Advisor "Jhunjhunwala, Siddharth"
Now showing items 1-6 of 6
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Cues for phagosome maturation deciphered using a tuneable particulate system
Phagocytosis, an essential component of the innate immune response, is followed by the process of phagosome maturation inside the cell. Maturation ensures that the engulfed target is delivered to the acidic lysosome for ... -
Delineating the dynamics of neutrophil response in multiple inflammatory stimuli and its consequences
In this thesis, we investigate the regulation of neutrophils, an important component of the immune system, and its implications on inflammation and pathological conditions. We use biomaterial implants to induce chronic ... -
Engineering Graphene Oxide Surface Chemistry and Investigating Its Effect on The Physicochemical and Biological Properties
In the current study, systematic tuning of oxidation degree of GO has been explored and a two-step methodology for engineering GO surface chemistry was successfully developed. The investigation of the effects of oxidation ... -
Immune cell surveillance and death on silicone catheter surfaces drives bacterial biofilm formation
Silicone venous catheters are among the most used medical devices in the world with a prevalence of up to 80% in hospitalised patients. While they are used for several life-saving applications, they are also prone to ... -
Improving Healing Outcomes in Diabetic Wounds by Understanding and Modulating Immune Responses
Diabetic Foot Ulcers (DFUs) are chronic wounds that show delayed or absence of healing in individuals with diabetes. Currently, diabetic wounds are managed clinically through regular debridement, pressure off-loading, ... -
Towards a Better Understanding of the Interaction between Phagocytic Immune Cells and Synthetic Particulates
Particulate technology has transformed the field of diagnostic and therapeutic medicine due to the ability of particulates to provide better contrast in various imaging modalities and improve the targeting of therapeutic ...