Biochemistry (BC): Recent submissions
Now showing items 241-259 of 259
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Towards The Understanding Of The Structural Biology Of Histone H1
(Indian Institute of Science, 2005-11-23)In the eukaryotic nucleus, an immense length of DNA is compactly packaged to generate an ordered three-dimensional hierarchical structure called chromatin (van Holde, 1988; Wolffe, A.P, 1998). This organization forms a ... -
Developmental And Functional Regulation Of DNA Topoisomerase II in Postnatal Rat Testis
(Indian Institute of Science, 2005-11-23)Characterization of the polyoma virus chromosome as a circular, double-stranded, supercoiled DNA (Weil and Vinograd, 1963; Vinograd et al.,-1965) made it apparent that the DNA enzymatic machinery faces a formidable problem ... -
Studies On Cloning And Characterization Of GnRH Receptor From The Pituitary Of Bonnet Monkey (Macaca Radiata) And Functional Studies With The Antiserum To GnRH Receptor
(Indian Institute of Science, 2005-11-23)GnRH is a decapeptide hormone, which plays a major role in the process of mammalian reproduction. It is synthesized by the hypothalamus and binds to its cognate receptor on the pituitary, to bring about the release of ... -
Transcriptional Regulation By Nuclear Receptor Homodimers Binding To The Direct Repeat Motif DR1 : Investigations In An in vitro Transcription System Derived From Rat Liver Nuclear Extracts
(Indian Institute of Science, 2005-11-23)Nuclear receptors (NRs) are important transcription factors involved in the regulation of a variety of physiological processes such as embryonic development, cell differentiation and homeostasis (for review, see Mangelsdorf ... -
Cytotoxic T lymphocyte Responses Against Japanese Encephalitis Virus In Mice: Specificity And Immunotherapeutic Value
(Indian Institute of Science, 2005-10-07)Cytotoxic T Lymphocytes (CTL) are known to play an important role in clearing infectious virus from infected hosts in a variety of viral infections. Depending on the type of virus and mode of virus entry both class I and ... -
Oxidative Stress In The Brain: Effects Of Hydroperoxides And Nitric Oxide On Glyceraldehyde 3-Phosphate Dehydrogenase And Phosphoinositide Cycle Enzymes
(Indian Institute of Science, 2005-09-01)In the aerobic cell, oxygen can be converted into a series of reactive metabolites, together called as "reactive oxygen species" (ROS). This large group include both radical and non-radical species such as superoxide anion ... -
Antigenic Determinants Of Chicken Riboflavin Carrier Protein: Structural And Functional Aspects
(Indian Institute of Science, 2005-09-01)Investigations detailed in this thesis constitute a part of the continuing programme of research undertaken in our laboratory on the riboflavin carrier protein (RCP) with particular reference to identification and synthesis ... -
Mycobacterium tuberculosis RecA intein, a novel LAGLIDADG homing endonuclease, displays dual target specificity in the presence of alternative cofactors
(Indian Institute of Science, 2005-05-10)Mobile inteins and introns are genetic elements capable of self-propagation by “homing” into host genes and occur in entire taxonomy: eubacteria, eukarya, archaea and viruses. The process of “homing” is promoted by an ... -
Immunochemical Studies on the family of Biotin Binding Proteins
(Indian Institute of Science, 2005-04-29)Investigations detailed in this thesis constitue a part of continuing programme of research work undertaken in this laboratory on vitamin binding proteins. Avidin from the chicken egg white, streptavidin &om the bacterium ... -
Cloning and Expression of a Diagnostic Antigen for Invasive Amoebiasis
(Indian Institute of Science, 2005-04-29)A crude extract of axenically grown amoebae was used as antigen in order to develop an AB microELISA for the detection and quantitation of E. histolytica-specific IgG antibodies. This ELISA was used to screen individual ... -
Invertase in a thermophilic fungus, thermomyces lanuginosus: its unusual behaviour And regulation
(Indian Institute of Science, 2005-04-25)The understanding of the phenomenon of thermophily requires investigations of both thermophilic prokaryotes and eukaryotes. In the eukaryotes, thermophily is exhibited only by a few species of fungi which can grow up to ... -
Identification of Tropomyosin as the Major Cross-Reacting Crustacean Allergen
(Indian Institute of Science, 2005-04-25)Seafood including crustaceans, on ingestion, are known to provoke gastrointestinal as well as systemic allergic reactions. Crustaceans are aquatic arthropods with a chitinous exoskeleton and include shrimp, lobster, prawn ... -
Hormones and Cuscuta Development Abscisic Acid And Its Conjugates-Endogenous Levels And Metabolism During Growth And Haustoria Formation
(Indian Institute of Science, 2005-04-25)Cuscuta or dodder is one of the best known higher plant parasite with around 158 species over 5 continents parasitising a wide variety of host plants (Yuncker,1932) Dodders are characterised by their interesting parasitic ... -
Gene Expression During Cytokinin-Induced Haustoria Formation in Cuscuta Reflexa, Roxb
(Indian Institute of Science, 2005-04-19)How multicellular organisms develop from a single-celled fertilized egg or zygote that in no way resembles the adult form is one of the major challenges in biology The phase of rapid cell division that follows fertilization ... -
Functions Of Nucleosomes And Other Regulatory Factor(S) In Homologous Recombination Promoted By RecA Protein
(Indian Institute of Science, 2005-04-18)Homologous genetic recombination occurs during the life cycle of virtually every organism Genetic studies especially in prokaryotes and fungi have defined the rules of recombination, led to the characterization of alternate ... -
Fatty Acid And Triacylglycerol Synthesis In Developing Seeds Of Groundnut (Arachis Hypogaea) And Pisa (Actinodaphne Hookeri)
(Indian Institute of Science, 2005-04-18)The term "lipid" covers an extremely diverse range of chemical or molecular species. Lipids, defined as molecules that are sparingly soluble in water but readily soluble in organic solvents, are broadly categorized into ... -
Characterisation Of DNA Llgase And Pairing Activities From A Partially Purified Fraction From Rat Testis
(Indian Institute of Science, 2005-04-06)Homologous genetic recombination is a central feature of meiosis in most sexually dividing organism. It leads to the establishment of new linkage relationships between genes and is crucial for the successful completion of ... -
Biodegradation Of 1-Naphthoic Acid
(Indian Institute of Science, 2005-04-06)Polycyclic aromatic hydrocarbons (PAHs) are compounds containing carbon and hydrogen atoms of fused benzene rings in linear, angular or cluster arrangements. These compounds have a large (negative) resonance energy, resulting ... -
Amylases From A Thermophilic Fungus Thermomyces Lanuginosus Iisc 91 :Their Purification And Properties
(Indian Institute of Science, 2005-04-06)A knowledge of molecular properties and structure of heat-stable enzymes is important for the understanding of basic principles governing thermo stability of proteins and evolution of life at high temperatures. Information ...