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    The dual-targeting of Saccharomyces cerevisiae Pso2 into the nucleus and mitochondria is regulated by post-translational modifications: Implications for organelle-specific DNA repair 

    Somashekara, S C
    The repair of DNA interstrand crosslinks (ICLs) involves the concerted action of multiple DNA repair pathways. In eukaryotes, ICLs are sensed and repaired by replication-coupled or replication-independent mechanisms in ...

    Understanding the architecture of mitochondrial presequence translocase machinery and its implications in ALS progression 

    Waingankar, Tejashree Pradip
    The current thesis describes the structural organization of the presequence translocase machinery and its functional association with ALS pathogenesis. The TIM23 complex is essential for the mitochondrial biogenesis of ...

    Understanding the role of mtHsp70 in regulating mitochondrial homeostasis: revealing its significance in Congenital Sideroblastic Anemia progression 

    Vishwanathan, Vinaya
    Mitochondria are ubiquitous organelles placed at the nexus of several metabolic and signaling pathways essential for cell survival. Therefore, maintaining a healthy and functional organelle becomes paramount for the cell. ...

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    AuthorSomashekara, S C (1)Vishwanathan, Vinaya (1)Waingankar, Tejashree Pradip (1)Subject
    Mitochondria (3)
    NATURAL SCIENCES (3)ALS pathogenesis (1)Chaperone (1)Congenital Sideroblastic Anemia (1)DNA interstrand crosslinks (1)mtHsp70 (1)Nucleus (1)Protein Quality Control (1)protein translocation (1)... View MoreHas File(s)Yes (3)

    etd@IISc is a joint service of SERC & J R D Tata Memorial (JRDTML) Library || Powered by DSpace software || DuraSpace
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