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Heat Shock Protein 70 Of Plasmodium Falciparum: Proteomic Analysis Of Its Complexes And Cellular Functions
(Indian Institute Of Science, 2004-10)
Hest shock protein 70 (Hsp70) class of chaperones is highly conserved and present ubiquitously in all cellular organisms They play important role in folding of nascent polypeptides and translocation of precursor proteins ...
Mycobacterium tuberculosis RecA intein, a novel LAGLIDADG homing endonuclease, displays dual target specificity in the presence of alternative cofactors
(Indian Institute of Science, 2005-05-10)
Mobile inteins and introns are genetic elements capable of self-propagation by “homing” into host genes and occur in entire taxonomy: eubacteria, eukarya, archaea and viruses. The process of “homing” is promoted by an ...
Peptidase N, A Major Aminopeptidase Belonging To The M1 Family : Biochemical And Functional Implications
(2009-08-05)
Intracellular protein degradation is required for maintaining the cellular proteome and regulating cellular processes. This pathway involves proximal ATP-dependent proteases that unfold and translocate proteins targeted ...
Type-II Ribosome Inactivating Proteins From Abrus Precatorius : Cytotoxicity And Mechanism Of Cell Death
(2009-05-21)
Type-II Ribosome Inactivating Proteins from Abrus precatorius: Cytotoxicity and Mechanism of Cell Death
A/B toxins produced by bacteria and plants are among the deadliest molecules known. The plant type-II ribosome ...
Virus-Inducible Gene Expression Changes In Mouse Brain : Studies With Japanese Encephalitis & Rabies Viruses
(2009-04-16)
One of the key events in a virus-infected host cell is the activation and repression of a large number of host genes. In recent years, such differentially expressed host genes have been identified for several viruses, ...
Functional Role Of Heat Shock Protein 90 From Plasmodium Falciparum
(2009-03-18)
Molecular chaperones have emerged in recent years as major players in many aspects of cell biology. Molecular chaperones are also known as heat shock proteins (HSPs) since many were originally discovered due to their
increased ...
Diaminopropionate Ammonia Lyase : Characterization, Unfolding And Mechanism Of Inhibition By Aminooxy Compounds
(2009-03-13)
Diaminopropionate ammonia lyase (DAPAL) which belongs to the class of PLP enzymes is reported only from prokaryotes. It is involved in the removal of two amino groups from its substrate, diaminopropionate, to form ammonia ...
Insights Into Oxidative Folding Of Retinol Binding Protein In The Endoplasmic Reticulum : A Study In Isolated Microsomes
(2009-04-30)
The central role played by the Endoplasmic Reticulum (ER) in the correct folding and assembly of secretary and membrane proteins cannot be overstated. As the first compartment in the secretary pathway, it is responsible ...
Studies On Cloning And Characterization Of GnRH Receptor From The Pituitary Of Bonnet Monkey (Macaca Radiata) And Functional Studies With The Antiserum To GnRH Receptor
(Indian Institute of Science, 2005-11-23)
GnRH is a decapeptide hormone, which plays a major role in the process of mammalian reproduction. It is synthesized by the hypothalamus and binds to its cognate receptor on the pituitary, to bring about the release of ...
Immunochemical Studies on the family of Biotin Binding Proteins
(Indian Institute of Science, 2005-04-29)
Investigations detailed in this thesis constitue a part of continuing programme of research work undertaken in this laboratory on vitamin binding proteins. Avidin from the chicken egg white, streptavidin &om the bacterium ...