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    Production of taxol from Lasiodiplodia theobromae and biochemical characterization of its 10-deacetylbaccatin III-10-O-acetyltransferase enzyme and evaluation of anticancer activity of enzymatically synthesized baccatin III 

    Sah, Balendra
    Taxol (paclitaxel) originally identified from the inner bark of Taxus brevifolia, is a clinically approved anticancer drug for the treatment of various kinds of cancer, particularly ovarian cancer, breast cancer and Kaposi's ...

    A Ligase IV/XRCC4-dependent single strand break repair pathway for the maintenance of A/T-rich regions during DNA replication in mammals 

    kumari, Nitu
    The DNA in our cells is under constant threat from various exogenous and endogenous sources. To ensure error free and faithful transmission of hereditary material, human cells employ several DNA repair pathways. Mammalian ...

    Isolation, structure elucidation and increasing anticancer efficacy of an anti-cancer secondary metabolite from a marine-derived endophytic fungus, Aspergillus species 

    Taritla, Sidhartha
    Cancer is the leading cause of mortality globally, contributing to ~10 million fatalities in 2020, or roughly one in every six deaths, according to global cancer statistics 2020. Around 50% of all small molecules approved ...

    Uncovering of a novel non-taxane anticancer secondary metabolite from Taxol-producing endophytic fungus: Optimization of culture parameters and whole-genome sequence analysis for improved taxane production biosynthesis. 

    Singh, Satpal
    Cancer-related mortalities and morbidities have proven to be a great health burden for human society with immense economic implications. With uncontrolled proliferation of cells as the fundamental principle underlying its ...

    Exploring the role of low complexity protein sequence in regulating RNA granule dynamics and translation control 

    Roy, Raju
    RNA granules are conserved membraneless mRNP complexes that play an important role in determining mRNA fate by affecting translation repression and mRNA decay. Processing bodies (P-bodies) harbor enzymes responsible for ...

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    Authorkumari, Nitu (1)Roy, Raju (1)Sah, Balendra (1)Singh, Satpal (1)Taritla, Sidhartha (1)Subject
    Cancer (5)
    NATURAL SCIENCES (5)
    Taxol (2)anticancer (1)anticancer drug (1)anticancer drugs (1)AT rich fragile sites (1)carbon dots (1)DNA repair (1)endophytic fungus (1)... View MoreHas File(s)Yes (5)

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