Overexpression of BCL2 has been reported in several cancers, such as B-cell lymphomas, leukemias, colorectal adenocarcinoma, breast cancer, prostate cancer, and oral cancer, making it an excellent target for cancer treatment. ...

One year embargo upto 20/2/2026 RGG-motif containing proteins represent one of the major subsets of RNA-binding proteins characterized by the presence of RGG/RG repeats. These proteins have been associated with a wide ...

Interferons, initially discovered for their antiviral properties, play pivotal roles in various biological processes, including host defense against pathogens, tumor surveillance, and disease pathogenesis. Interferon-gamma ...

Cancer is the second leading cause of mortality globally, with over 6 million new cases diagnosed annually. Research on effective therapies is crucial due to the disease's complexity. Natural materials in chemotherapy have ...

All physical processes in living organisms are driven by specific biomolecular interactions. Elucidating the characteristics of biomolecular interactions between proteins and their respective small molecule ligands can ...

Williams-Beuren Syndrome (WBS) is a rare multisystem genomic disorder characterized by mild to moderate cognitive impairment, unique personality traits, distinctive facial features, cardiovascular problems, and infantile ...

Homologous recombination (HR) is a ubiquitous cellular process that occurs in all three domains of life as well as in DNA and RNA viruses. In eukaryotes, HR is critically important for homology-directed DNA repair (HDDR) ...

Chromatin is a dynamic structure that reorganizes to support proper transcription, replication, repair, and segregation. Principal chromosomal constituents that shape chromosomes are the SMC (Structural Maintenance of ...

Mammalian mRNAs generally have a 5'UTR (untranslated region), a coding DNA sequence, and a 3'UTR. The 3'UTR of mRNA is generally believed to be the untranslated region of the mRNA. However, there are certain instances ...

Erythrocytes are specialized cells that perform the crucial function of gas exchange in all vertebrates. Regulation of gene expression was believed to be absent in these cells due to the absence of nucleus. It was also ...