Browsing Biochemistry (BC) by Subject "Homologous recombination"
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Deciphering the biochemical and biophysical properties of the Holliday junction resolvases RuvC and RuvX from Mycobacterium smegmatis
Homologous recombination (HR) is a ubiquitous cellular process that occurs in all three domains of life as well as in DNA and RNA viruses. In eukaryotes, HR is critically important for homology-directed DNA repair (HDDR) ... -
Role of RTEL1 helicase in the regulation of homologous recombination during DNA replication
Homologous recombination (HR) plays an essential role in the repair of DNA double-strand breaks (DSBs), replication stress responses, and genome maintenance. Although the mechanism of HR has been extensively studied in the ... -
Understanding the Mechanism of DNA Double-Strand Break (DSB) Repair in Mitochondria and Various Mammalian Organs.
Various exogenous and endogenous agents can damage DNA. Exogenous agents include chemicals and radiation, such as ionizing radiations and UV rays, while endogenous agents include DNA replication errors, reactive oxygen ...