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    • Browsing Biochemistry (BC) by Subject
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    Browsing Biochemistry (BC) by Subject "Biochemistry"

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      • Adjunct Therapy with Curcumin for the Treatment of Malaria : Studies in a Murine Model 

        Dende, Chaitanya (2018-05-16)
        Malaria accounts for 198 million cases worldwide; with a high mortality rate. 584000 deaths were reported in 2013. Malaria is a re-emerging disease globally due to drug resistance, parasite recrudescence and non-availability ...
      • Anti-thrombotic Secondary Metabolites from Endophytic Fungi of Datura Metel and Cassia Fistula 

        Anantha Krishna, T H
        Blood coagulation is a process that occurs normally in an animal during bleeding, to prevent the loss of blood from the body and is assisted by two key players -blood platelets and coagulation factors particularly thrombin. ...
      • Antigenic Determinants Of Chicken Riboflavin Carrier Protein: Structural And Functional Aspects 

        Beena, T K (Indian Institute of Science, 2005-09-01)
        Investigations detailed in this thesis constitute a part of the continuing programme of research undertaken in our laboratory on the riboflavin carrier protein (RCP) with partic­ular reference to identification and synthesis ...
      • Biochemical and Functional Characterization of Mycobacterium Tuberculosis Nucleoid-Associated Proteins H-NS and mIHF 

        Harshavardhana, Y (2018-08-11)
        Bacteria lack nucleus and any other membrane-bound organelles. Hence all the cellular components, including proteins, DNA, RNA and other components are located within the cytoplasm. The region of the cell which encompasses ...
      • Biochemical Characterization Of Heat Shock Protein 90 From Plasmodium Falciparum 

        Pallavi, Rani (2013-06-07)
        Molecular chaperones are a group of proteins which maintain cellular homeostasis by assisting de novo protein folding and their refolding to native state after destabilization due to external stress. They are also known ...
      • Characterisation of Monoclonal Antibodies and Small Molecule Inhibitors as Hepatitis C Virus Entry Inhibitors 

        Bose, Mihika (2017-12-15)
        Hepatitis C virus (HCV) represents a global health threat. HCV is a blood-borne positive-strand RNA virus belonging to the Flaviviridae family that infects ~160 million people worldwide. About 70% of infected individuals ...
      • Characterization of mouse Apolipoprotein L9 and investigation of its cellular functions 

        Arvind, A
        This thesis is divided into 3 chapters. Chapter 1, titled General Introduction, is a chapter that familiarizes the reader with the general subject matter of the thesis so that the content of Chapters 2 and 3 can ...
      • Characterization Of Structural And Non-structural Proteins Of Positive Sense, Single-stranded RNA Plant Viruses 

        Mathur, Chhavi (2015-07-08)
        In the present thesis, two positive sense single-stranded RNA viruses have been used as models to understand the structure and function of viral-encoded proteins. One of them, Pepper Vein Banding Virus (PVBV; genus Potyvirus; ...
      • Characterization of Thymocyte Subpopulations and Mechanistic Insights during Various Modes of Thymic Atrophy 

        Majumdar, Shamik
        T lymphocytes along with B lymphocytes constitute the adaptive immune system, which is critical for host defence. The progenitors of T cells arise in the bone marrow and the sequential development of T cells occurs in the ...
      • Computational and Experimental Approaches to Protein Design 

        Nagarajan, Deepesh
        Protein design is a rapidly maturing field, with the goal of designing proteins with customized structures and functions. A large number of protein structures are experimentally determined, which have facilitated an ...
      • Cytosolic Lysophosphatidic Acid Acyltransferase : Implications in Lipid Biosynthesis in Yeast, Plants and Human 

        Ghosh, Ananda Kumar (2018-02-11)
        Cytosolic LPA acyltransferase in yeast An isooctane tolerant strain of S. cerevisiae KK-12 was reported to have increased saturated fatty acid content (Miura et. al., 2000). Amongst the various genes upregulated on isooctane ...
      • Delta-Aminolevulinic Acid Dehydratase From Plasmodium falciparum - Indigenous Vs Imported 

        Dhanasekaran, S (2011-05-02)
      • Developmental And Functional Regulation Of DNA Topoisomerase II in Postnatal Rat Testis 

        Bakshi, Rahul P (Indian Institute of Science, 2005-11-23)
        Characterization of the polyoma virus chromosome as a circular, double-stranded, supercoiled DNA (Weil and Vinograd, 1963; Vinograd et al.,-1965) made it apparent that the DNA enzymatic machinery faces a formidable problem ...
      • Diaminopropionate Ammonia Lyase : Characterization, Unfolding And Mechanism Of Inhibition By Aminooxy Compounds 

        Khan, Farida (2009-03-13)
        Diaminopropionate ammonia lyase (DAPAL) which belongs to the  class of PLP enzymes is reported only from prokaryotes. It is involved in the removal of two amino groups from its substrate, diaminopropionate, to form ammonia ...
      • Differential Role Of FSH : A Study Using Sertoli Cells And Epididymal Cells 

        Chitra Lekha, * (2011-08-19)
      • DNA Double-Strand Break Repair : Molecular Characterization of Classical and Alternative Nonhomologous End Joining in Mitochondrial and Cell-free Extracts 

        Kumar, Tadi Satish (2018-04-05)
        Maintenance of genomic integrity and stability is of prime importance for the survival of an organism. Upon exposure to different damaging agents, DNA acquires various lesions such as base modifications, single-strand ...
      • DNA Mismatch Repair In Haemophilus Influenzae : Characterization Of MutH, L, S And Their Interaction 

        Joseph, Nimesh (2011-05-03)
      • Dual Sites For Heme Biosynthesis In The Malarial Parasite 

        Varadharajan, S (2011-05-02)
      • Effect Of Glycodelin A On Cells Of The Immune System Insights Into GdA-Induced Signaling In Monocytes, B And NK Cells 

        Alok, Anshula (2010-04-06)
        Glycodelin is a 162 amino acid dimeric, glycosylated, secretory protein of the lipocalin superfamily. Its classification as a lipocalin(carriers of small hydrophobic molecules) is based mainly on the presence of lipocalin ...
      • Elucidating the Roles of Lon Protease and its Substrate, MarA, in Response to salicylate and other Compounds in Escherichia coli 

        Bhaskarla, Chetana (2017-11-28)
        Cytosolic protein degradation is crucial for cellular homeostasis as it orchestrates protein turnover by destruction of misfolded, unstable and abnormal proteins. This process has two main stages: (i) an ATP-dependent stage ...

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