Browsing Biochemistry (BC) by Author "Bhosle, Amrisha"
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A molecular systems approach to unravel mechanisms and targets in antifolate-resistant bacteria and cancers
Bhosle, AmrishaAntifolates such as trimethoprim (TMP) and methotrexate (MTX) widely used for treating bacterial infections and certain cancers respectively, inhibit dihydrofolate reductase (DHFR) in the folate pathway. However, the use ...