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Targeted Delivery of Cytotoxic Metal Complexes into Cancer Cells with and without Macromolecular Vehicles
(2018-04-12)
Anticancer active metal complexes such as cisplatin are routinely used for treating various cancers since 1978. However, the side effects of cisplatin overwhelm its therapeutic potential, especially in the latter stages ...
Vibrational Microspectroscopic Studies of Biomedical Conditions Using Model Systems
(2018-05-08)
Over the last century, despite enormous advancements in biomedical research and the development of sophisticated analytical instruments many diseases continue to be a burden on humankind particularly on the aged. This is ...
Physicochemical, Electrical and Electrochemical Studies on Titanium Carbide-Based Nanostructures
(2018-04-03)
Materials for studies related to nanoscience and nanotechnology have gained tremendous attention owing to their unique physical, chemical and electronic properties. Among various anisotropic nanostructures, one dimensional ...
Syntheses and Structure Elucidations of Ternary Metal (Cu/Co)Complexes with Nucleic Acid Constituents
(2018-05-07)
The thesis is divided into four chapters
Chapter 1 provides a brief introduction to the metal-nucleic acid interactions, the role of synthetic models to understand them with both solution (potentiometric) and solid state ...
Investigations on Azide Functional Polymers as Binders for Solid Propellants
(2018-05-09)
This thesis contains investigations in the area of polymers herein propellants binders are modified functionally to meet the requirements of future energetic propellants. Chapter 1 contains a broad introduction to the area ...
Functional Hyperbranched Polyethers Via Melt-Transetherification Polymerization
(2010-04-12)
Dendrimers are highly branched macromolecules which are prepared by a stepwise procedure. The presence of a well-defined core, discrete generations and a large number of terminal groups in dendrimers make them structurally ...
Controlling Conformation of Macromolecules by Immiscibility Driven Self-Segregation
(2018-05-09)
Controlling conformation of macromolecules, both in solution and solid state, has remained an exciting challenge till date as it confronts the entropy driven random coil conformation. Folded forms of biomacromolecules, ...
Nanoparticle Mediated Suppression of Protein Aggregation
(2018-05-11)
The increasing demands for biopharmaceuticals to treat different diseases have raised concerns about controlling the quality and efficacy of such pharmaceuticals. The design and formulation of a stable protein or peptide ...
Theoretical Studies of Energy Transport in Complex Systems
(2018-05-09)
Photosynthesis involves the absorption of photons by light-harvesting pigments and the subsequent transfer of excitation from the absorption centre to the reaction centre. This highly efficient phenomenon of excitation ...
First Hyperpolarizability (β) of Organic and Inorganic Compounds : Keto-Enol Tautomerism and Halogen Effect
(2018-05-09)
The work presented in this thesis has broadly established a few findings about the structure¬hyperpolarizability relation in molecular compounds: First, by measuring βHRS of an organic keto-enol tautomer, benzoylacetanilide ...