Browsing Inorganic and Physical Chemistry (IPC) by Subject "Medicinal Chemistry"
Now showing items 1-7 of 7
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Nitrite Releasing Molecules: Synthesis, Mechanism and Potential Application as Prodrugs for the Improvement of Nitric Oxide Bioavailability
The thesis titled “Nitrite Releasing Molecules: Synthesis, Mechanism and Potential Application as Prodrugs for the Improvement of Nitric Oxide Bioavailability“ aimed at the development of strategies for the improvement of ... -
Redox Active Antioxidant Nanozymes as Potential Antithrombotic and Antiviral Agents
Reactive oxygen species (ROS), such as superoxide (O2-) hydrogen peroxide (H2O2), and hydroxyl radicals (.OH), generated as a result of cellular metabolism, play a multitude of physiological roles. They play key roles in ... -
Studies on BODIPY-conjugates of Copper and Zinc for Cellular Imaging and Photodynamic Therapy
Cancer is a dreadful disease that occurs due to the uncontrolled division of abnormal cells. Though there are different therapeutic modalities available for cancer, chemotherapy is considered as the most practiced method. ... -
Studies on Near-IR Light Photocytotoxic Oxovanadium Complexes
(2018-04-11)The present thesis deals with different aspects of the chemistry of oxovanadium(IV) complexes, their interaction with double stranded DNA, photo-induced DNA cleavage, photo-enhanced cytotoxicity in visible light and red ... -
Studies on Photocytotoxic Ferrocenyl Conjugates
(2018-01-28)The present thesis deals with different aspects of the chemistry and photo-biology of various ferrocene-conjugates, their interaction with double helical DNA, DNA photocleavage and photo-enhanced cytotoxicity in visible ... -
Targeted Delivery of Cytotoxic Metal Complexes into Cancer Cells with and without Macromolecular Vehicles
(2018-04-12)Anticancer active metal complexes such as cisplatin are routinely used for treating various cancers since 1978. However, the side effects of cisplatin overwhelm its therapeutic potential, especially in the latter stages ... -
Targeting Cancer Cells And Live Cell Imaging Using Bis(thiosemicarbazone) Complexes Of Copper And Zinc
(2016-02-25)Transition metal bis(thiosemicarbazone) complexes have been of great interest in the last five decades. One of the most striking features of these complexes is that they possess a wide range of biological properties including ...