Browsing Inorganic and Physical Chemistry (IPC) by thesis submitted date"2025"
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Activation of H–E (E = H, Si, B, C) σ-Bond by Iridium and Rhodium Pincer Complexes: Implications in Catalytic (De)hydrogenation Reactions
Methane is a major constituent of natural gas and crude oil. Due to its abundance, methane is attractive from the standpoint of its utilization and conversion into value-added products.1 This process involves activation ... -
Chemical Modulation of Ferroptosis in Mammalian Cells by Synthetic Organoselenium and Gold-based Small Molecules
Oxidative stress induced by reactive oxygen species (ROS) plays a crucial role in triggering various forms of cell death, including apoptosis, autophagy, and necrosis. In recent years, a distinct and regulated form of cell ... -
Design and Development of Hybrid Catalyst for Hydrogen Storage: A Demonstrative Concept using Liquid Organic Hydrogen Carriers (LOHCs)
The urgent need to address CO2 emissions resulting from the industrial revolution has placed a strong emphasis on the reduction of greenhouse gases. As a result, hydrogen has gained significant attention as a sustainable ... -
Design and development of proteasome inhibitors with improved efficacy in breast cancer cells: 3D tissue models and detailed molecular mechanistic studies
The proteasome is an enzyme complex that regulates the degradation of intracellular proteins, maintaining cell cycle regulation, protein quality, and cellular homeostasis. Proteasome inhibition has gained popularity as a ... -
Design Strategies for Janus and Core–Shell Structures and Single- Ion Conducting Membranes Based on Hyperbranched Polymers
Hyperbranched polymers (HBPs) are a class of highly branched macromolecules characterized by their low melt viscosity, high solubility, and numerous terminal functional groups amenable to chemical modification.1 Janus ... -
Enzymatically Combating Biofilm Associated Microbial Infections: Towards Next-Gen Enzyme-Based Therapeutics
Bacteria employ various defense mechanisms, one of the most significant being forming biofilms─structured communities of microorganisms encased in a self-produced extracellular polymeric substance (EPS) matrix. The widespread ... -
Exploring Single-Chain Collapse Transition in Periodically Grafted Amphiphilic Polymers
Synthetic polymers that emulate the complexity and responsiveness of biological macromolecules are at the forefront of modern materials research. One challenge in this field is to design polymer systems that can fold or ... -
Genetic Code Expansion with Unnatural Amino Acids: Biosynthesis and Incorporation of Halogen and Chalcogen-containing Amino Acids into Proteins
Genetic code expansion (GCE) strategy allows incorporation of unnatural amino acids (UAAs) with diverse physical, chemical, and biochemical properties. Multiple UAAs have been successfully incorporated co-translationally ... -
Guest Induced Structural Transformations of Coordination Cages and their Role in Mediating Chemical Conversions
Enzymes utilize several non-covalent interactions to perform catalytic reactions within small cavities. Coordination driven self-assembly has been found to be the simplest approach for constructing artificial enzyme ... -
Host-Guest Chemistry of Water-Soluble Coordination Cages and their Applications
Host-guest interactions are key to enzyme-substrate recognition, where the enzyme acts as a host, providing a specific cavity for the guest to bind. Inspired by host-guest interactions observed in nature, a significant ... -
Itaconate Based Dual-reactive Polymeric Coatings and Photo-cross-stitching Studies of Periodically Grafted Amphiphilic Systems
Dual-reactive coatings are those that covalently anchor to the substrate while at the same time permit installation of desired segments in a post-coating step; several approaches have been developed to design such polymers ... -
Mixed Metal Oxide Electrodes for Oxygen Evolution Reaction
This thesis explores transition metal oxide catalysts for the oxygen evolution reaction with a specific focus on cobalt and copper oxides. CoOx is well recognized for it’s OER activity, while CuOx received less attention. ... -
Nano-engineering in Ionic Liquid: From Fundamentals to Advanced Catalysis
Harnessing nanostructured materials of metals has led to the development of various synthetic methodologies. Although various strategies have been developed, challenges still remain obtaining desired shape, size, and ... -
Nitrite Releasing Molecules: Synthesis, Mechanism and Potential Application as Prodrugs for the Improvement of Nitric Oxide Bioavailability
The thesis titled “Nitrite Releasing Molecules: Synthesis, Mechanism and Potential Application as Prodrugs for the Improvement of Nitric Oxide Bioavailability“ aimed at the development of strategies for the improvement of ... -
Nucleophilic Boron Chemistry: Catalytic approaches to C-X (X= Br, Cl, O, N) Bond Activation in Metal/Metal-free Conditions
The boron-carbon bond occupies a central position in organic synthesis, functioning as a versatile “universal connector” to a broad range of functional groups. As a result, organoboranes have become indispensable synthetic ... -
Oxygen Reduction Reaction on Copper Oxide Electrodes Doped with First-Row Transition Metals
The oxygen reduction reaction (ORR) is critical in electrochemical applications such as fuel cells, metal-air batteries, and industrial processes like chlor-alkali and H2O2 synthesis. Its universality lies in the fact that ... -
Redox Active Antioxidant Nanozymes as Potential Antithrombotic and Antiviral Agents
Reactive oxygen species (ROS), such as superoxide (O2-) hydrogen peroxide (H2O2), and hydroxyl radicals (.OH), generated as a result of cellular metabolism, play a multitude of physiological roles. They play key roles in ... -
Regioselective Di- and Tri-Fluoromethylative Difunctionalization of Olefinic Bonds Driven by Homolysis, Ionic and Single Electron Transfer Mechanisms
The transition metal free and additive free difunctionalization of carbon-carbon olefinic bonds through di-and tri-fluoromethylation serve as a potent method for simultaneously introducing two functional groups across ... -
A Simple Scalable Route for the Production of Magnetic Nanomaterials and their Application in Wastewater Remediation
Superparamagnetic Iron Oxide Nanoparticles (SPIONs) have found extensive applications in diverse fields that include biomedicine, water remediation, and drug delivery. These applications require the development of synthetic ... -
Single Molecular Break Junctions: Insights into Charge Transport and Chemical Reactivity
Molecular electronics leverages the unique quantum transport properties of single molecules or molecular assemblies to create nanoscale components with tailored functionalities. Constructing a detailed knowledge base of ...