Browsing Division of Chemical Sciences by Title
Now showing items 173-192 of 1480
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Cytotoxicity of Metal Based Anticancer Active Complexes and their Targeted Delivery using Nanoparticles
(2018-02-21)Use of metal based anticancer medication began with the clinical approval of cisplatin in 1978. Research led to the development of six platinum based drug candidates which are in use around the world. However there is a ... -
Defect Engineering and Doping of 2D Transition Metal Dichalcogenides: A First-Principles Study
The foundation of the electronic industry is based on n-type and p-type semiconductor materials, which is obtained by the ubiquitously present point defects. The presence of defects affects the electronic and optoelectronic ... -
Deiodination of Thyroid Hormones by Iodothyronine Deiodinase Mimics
(2018-03-26)Thyroxine is the main secretory hormone of thyroid gland and it is produced in thyroglobulin by thyroid peroxidase/hydrogen peroxide/iodide system. After biosynthesis and secretion of thyroxine, it undergoes multiple ... -
Delayed Luminescent Materials: Development and Exploration of Applications
Delayed luminescence (DL) refers to light emission that persists after the excitation source is removed. Differing from conventional fluorescence, DL has a considerably longer lifetime attributable to the slow exciton ... -
Density matrix renormalization group studies of low-dimensional magnetic systems and conjugated polymers
To conclude, we have performed symmetrized DMRG calculations on the extended Hubbard–Peierls model. We have presented the dependences of exciton binding energy both on alternation ? and nearest-neighbor interaction parameter ... -
Design And Access To Disallowed And Unusual Conformers Of Peptides In Crystals And In Solution : Structural Consequences Of The Imidate And Thioimidate Isosteres For The Peptide Bond
(2016-03-04)This thesis entitled “Design and Access to Disallowed and Unusual Conformers of Peptides in Crystals and in Solution: Structural Consequences of the Imidate and Thioimidate Isosteres for the Peptide bond” is divided into ... -
Design and Application of Bile-Salt/Lanthanide Based Hydrogels
(2018-03-24)Chapter 1: Introduction to the luminescent properties of lanthanides Luminescence properties of trivalent lanthanides have been explored extensively over the past few decades owing to their unique properties. Lanthanides ... -
Design and Application of Self-Assembled Coordination Cages for Catalysis and as Drug Carrier
In summary the present thesis accounts for the design and synthesis of various coordination cages formed through the self-assembly reaction of the newly designed pyridine and pyrimidine based ligands with various 90° ... -
Design And Characterization Of Superamolecular Gels And Organic/Inorganic Composite Materials
(2013-06-24)Chapter 1. A Brief Overview of Low Molecular Mass Gels and their Applications This chapter deals with molecular gels derived from the self-assembly of small organic molecules (typical molecular weight < 2000 daltons), ... -
Design and Development of Hybrid Catalyst for Hydrogen Storage: A Demonstrative Concept using Liquid Organic Hydrogen Carriers (LOHCs)
The urgent need to address CO2 emissions resulting from the industrial revolution has placed a strong emphasis on the reduction of greenhouse gases. As a result, hydrogen has gained significant attention as a sustainable ... -
Design and Development of Metal-free Cross Dehydrogenative Coupling Reactions for the Construction of C-S, C-O and C-C bonds
(2018-06-13)The thesis entitled “Design and Development of Metal-Free Cross Dehydrogenative Coupling Reactions for the construction of C-S, C-O and C-C bonds” is divided into three Chapters. Chapter 1 is presented in five parts, which ... -
Design and Development of Microstereolithography (MSL) System and Its Applications in Microfabrication of Polymer and Ceramic Structures
(2017-11-30)In the present era where MEMS (Micro Electro-Mechanical Systems) technology is in¬evitable from the perspective of applications in non-silicon based micro-devices (such as biosensors, microfluidics, microvalves etc.), it ... -
Design and Development of Proteasome Activity Modulators: A Novel Strategy for the Treatment of Diabetes Mellitus
Design and Development of Proteasome Activity Modulators: A Novel Strategy for the Treatment of Diabetes Mellitus Abstract The ubiquitin-proteasome system (UPS) is the major pathway for degradation of the intracellular ... -
Design and development of proteasome inhibitors with improved efficacy in breast cancer cells: 3D tissue models and detailed molecular mechanistic studies
The proteasome is an enzyme complex that regulates the degradation of intracellular proteins, maintaining cell cycle regulation, protein quality, and cellular homeostasis. Proteasome inhibition has gained popularity as a ... -
Design And Development Of Synthetic Methods Using Metal-Mediated And Metal Free Redox Reactions : Novel C-H Activations, Reductions And Oxidative Transformations
(2016-02-16)The thesis entitled “Design and Development of Synthetic Methods using Metal-mediated and Metal-free Redox Reactions: Novel C-H Activations, Reductions and Oxidative Transformations” is presented in 4 chapters Chapter ... -
Design and Syntheses of Triarylborane Decorated Luminescent Dyes : Intriguing Optical Properties and Anion Sensing Applications
(2018-05-08)The main thrust of this thesis is the development of new triarylborane containing luminescent molecules as well as utilizing triarylboron center as a receptor for the selective detection of biologically, environmentally ... -
Design And Synthesis Of Benzimidazole Based Templates In Duplex And Quadruplex DNA Recognition And In Topoisomerase Inhibition
(2009-08-19)The thesis entitled “Design and Synthesis of Benzimidazole Based Templates in Duplex and Quadruplex DNA Recognition and in Topoisomerase Inhibition” deals with the design and synthesis of several benzimidazole based molecules ... -
Design And Synthesis Of Bile Acid Derived Oligomers And Study Of Their Aggregation And Potential Applications
(2015-01-14)Chapter 1: Amphiphilic self-assembled systems as nanocarriers Nanocarriers are the nanometric size molecular assemblies that are used for the transport of small molecules into their non-solvating environments. These ... -
Design and Synthesis of Cyclic Diselenides and Selenenyl Sulfides for Biomimetic Applications
Hydrogen peroxide (H2O2) plays important roles in cell signaling and redox reactions. However, elevated levels of H2O2 and organic peroxides induce oxidative stress, resulting in damage to biomolecules such as DNA, ...