Division of Biological Sciences: Recent submissions
Now showing items 801-820 of 1093
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Understanding Heat Shock Protein 90 Biology And Exploring Its Potential As A Target Against Neglected Protozoan Diseases
(2013-04-04)Cells invest a lot of energy in order to get their proteins to fold correctly and attain functionality. It is the functional proteome of a cell that defines the ‘life of a cell’. Cells have therefore employed dedicated ... -
Functional Characterization And Regulation Of UvrD Helicases From Haemophilus Influenzae And Helicobacter Pylori, And Recj Exonuclease Fron Haemophilus Influenzae
(2013-04-01)DNA repair processes are crucial for mutation avoidance and the maintenance of genetic integrity in all organisms. Organisms rely on repair processes to combat genotoxic stress imposed by hostile host environment, and ... -
Ants, Figs, Fig Wasps : The Chemical Ecology Of A Multitrophic System
(2013-04-01)Plant–animal interaction systems are complex food webs where the members—plants, pollinators, herbivores, parasites and predators of the pollinators/herbivores—interact with each other in ways which maximize their own ... -
Studies On The Structural And Biological Properties Of Rotavirus Enterotoxigenic Non-structural Protein 4 (NSP4)
(2013-04-01)Rotavirus is the major cause of infantile gastroenteritis. Each year more than 600,000 young children are estimated to die in developing countries throughout the world. Rotavirus infection can be either symptomatic or ... -
Evolutionary Design Of Active Site Plasticity In R.KpnI For Promiscuity In Metal Ion Utilization And Substrate Recognition
(2013-03-27)Restriction modification (R-M) systems are important components of the prokaryotic arsenal against invading genomes. R-M systems directly target the foreign DNA and are often considered as primitive immune systems in ... -
Phylogeny And Biogeography Of Hemidactylus Oken, 1817 Geckos Of The Indian Subcontinent
(2013-02-25)Geckos of the genus Hemidactylus Oken, 1817 are one of the most widely distributed and species-rich groups of gekkonids. With approximately 90 species, the genus Hemidactylus accounts for 10% of the total number of species ... -
Promoter Prediction In Microbial Genomes Based On DNA Structural Features
(2013-02-25)Promoter region is the key regulatory region, which enables the gene to be transcribed or repressed by anchoring RNA polymerase and other transcription factors, but it is difficult to determine experimentally. Hence an ... -
Structural Studies On The Rotaviral Enterotoxin NSP4
(2013-02-12) -
A Study On The Mechanism Of Initiator tRNA Selection On The Ribosomes During Translation Initiation And Rescue Of The Stalled Ribosomes By SsrA In Escherichia Coli
(2013-02-07)The studies reported in this thesis describe the work done in the area of translation initiation where a previously unknown role of multiple copies of initiator tRNA in E. coli has been reported. Also the role of SsrA ... -
Protein-DNA Graphs And Interaction Energy Based Protein Structure Networks
(2013-01-29)Proteins orchestrate a number of cellular processes either alone or in concert with other biomolecules like nucleic acids, carbohydrates, and lipids. They exhibit an intrinsic ability to fold de novo to their functional ... -
Cyclic AMP In Mycobacteria Adenylyl Cyclases And Cyclic AMP Receptor Proteins
(2013-01-28)The discovery of cyclic AMP (cAMP), nearly 50 years ago by Sutherland radically altered the appreciation of metabolic regulation. Since then the presence of cAMP and its tremendous physiological impact has been demonstrated ... -
Mechanism Of Activation Of Bacteriophage Mu Late Genes By Transcription Activator Protein C
(2013-01-24)Initiation of transcription is a major step in the regulation of gene expression. A dominant theme in regulation of gene expression lies in understanding the mechanism involved in selective expression of the genes in ... -
Topology-based Sequence Design For Proteins Structures And Statistical Potentials Sensitive To Local Environments
(2013-01-17)Proteins, which regulate most of the biological activities, perform their functions through their unique three-dimensional structures. The folding process of this three dimensional structure from one dimensional sequence ... -
Structural, Biophysical And Biochemical Studies On Mannose-Specific Lectins
(2013-01-17)For a long time, the scientific community underestimated the value of carbohydrates and the approach of most scientists to the complex world of glycans was apprehensive. The scenario, however, has changed today. With the ... -
Physiological Importance Of DNA Repair In Mycobacteria
(2013-01-16) -
Studies On Endocrine And Behavioral Assessment Of Reproductive Status In Asian Elephants (Elephas Maximus)
(2013-01-16)The Asian elephant (Elephas maximus), a charismatic ‘flagship species’, is threatened by extinction in the wild, and the development of self-sustainable captive populations is a key conservation challenge. A third of the ... -
Divided They Stay : Species Coexistence In A Community Of Mutualists And Exploiters
(2012-12-14)The fig–fig wasp interaction is a classic example of obligate mutualism and coevolution. It is also a nursery pollination mutualism and supports a diversity of exploiter/parasite/non-pollinating fig wasp species. Mutualists ...