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Genome-Wide And Structural Analyses Of Protein Kinase Superfamily
(2010-04-12)
A signal transduction process refers to chain of highly regulated biochemical steps which results in the transfer of signal in response to a stimulus in the extracellular environment to the intracellular compartments such ...
Structure Function Relationship In Tryptophanyl tRNA Synthetase Through MD Simulations & Quantum Chemical Studies On Unusual Bonds In Biomolecules
(2010-10-21)
Biological processes are so complicated that to understand the mechanisms underlying the functioning of biomolecules it is inevitable to study them from various perspectives and with a wide range of tools. Understanding ...
Studies On DNA Mismatch Repair Nicking Endonucleases Of Haemophilus Influenzae And Neisseria Gonorrhoeae
(2010-01-01)
DNA mismatch repair ensures faithful transmission of genetic material from parents to progeny, which is required for the survival of the organism. The studies on E. coli MMR proteins have formed the basis for the study ...
New Active Site Fold And The Role Of Metal Ions In Structure Function Relationship Of A Promiscuous Endonuclease - R.KpnI
(2010-07-08)
Bacteria employ survival strategies to protect themselves against foreign invaders, including bacteriophages. The ‘immune system’ of bacteria relies mostly on restriction-modification (R-M) systems. The primary role of R-M ...
Molecular Actions Of Arecoline, An Alkaloid Implicated In The Manifestation Of Oral Submucous Fibrosis (OSMF)
(2010-07-21)
The pathogenesis of oral submucous fibrosis (OSMF) is due to a complex interplay between the production and degradation of extracellular matrix (ECM) protein components. In tissue fibrosis, there is a net accumulation of ...