Browsing Division of Biological Sciences by Subject "Lectins"
Now showing items 1-17 of 17
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Crystal Structure Of Jacalin At 3.0A Resolution
(2012-11-15) -
Energetics Of Protein-Carbohydrate Recognition
(Indian Institute of Science, 2006-04-28)The work embodied in this thesis pertains to an attempt to understand better, the molecular basis of protein-carbohydrate recognition. For this purpose a systematic study was undertaken, not only of the energetics of ... -
First thorough characterization of the structure, interactions and specificity of an archeal lectin with implication for TB infection
Decades long studies on plant lectins carried out in this laboratory have contributed substantially to glycobiology and helped in the initiation and development of macromolecular crystallography in India. Subsequently the ... -
Further Structural Studies on Jacalin and Genomics Search for Mycobacterial and Archeal Lectins
(2017-12-03)This thesis consists of two parts. The first part is concerned with further structural and related studies of jacalin, one of the two lectins found in jack fruit seeds. The second part deals with the search of mycobacterial ... -
Garlic (Allium Sativum) Agglutinin I: Specificity, Binding And Folding Mechanism
(Indian Institute of Science, 2006-11-08)Lectins are a class of proteins that bind to carbohydrates with a high degree of specificity. They are involved in various cellular processes such as, host - pathogen interactions, targeting of proteins within cells, cell ... -
Molecular Characterization of Mannose Binding Lectins
Lectins are proteins of non-immunologic origin that bind to carbohydrates with high fidelity. They constitute a large class of multivalent recognition molecules that specifically interact with their cognate sugar moieties ... -
Structural and Related Studies on Mycobacterial Lectins
(2018-05-09)This thesis is concerned with the first ever X-ray crystallographic and complimentary solution studies on mycobacterial lectins. Lectins, described as multivalent carbohydrate binding proteins of non-immune origin, are ... -
Structural Investigations Of Sugar-Binding And Multivalency In Peanut Lectin
(2009-03-04)Starting with the structure analysis of ConA in the 70s, the crystal structures of hundreds of different lectins and their carbohydrate complexes have been determined. Lectins, multivalent carbohydrate-binding proteins ... -
Structural Studies on Non-toxic Homologues of type II Ribosome Inactivating Proteins (RIPs)
This thesis is concerned with structural and related studies on two non-toxic homologues of type II RIPs. Type II RIPs, which are more toxic than type I, contain an additional lectin chain (B-chain) covalently linked to ... -
Structural Studies On Winged Bean Agglutinins
(Indian Institute of Science, 2007-01-11)Lectins are multivalent carbohydrate binding proteins that specifically recognise diverse sugar structures and mediate a variety of biological processes, such as cell-cell and host-pathogen interactions, serum glycoprotein ... -
Structural, Biophysical And Biochemical Studies On Mannose-Specific Lectins
(2013-01-17)For a long time, the scientific community underestimated the value of carbohydrates and the approach of most scientists to the complex world of glycans was apprehensive. The scenario, however, has changed today. With the ... -
Structure analysis of lectin and lectin-like domains from Entamoeba histolytica
Lectins are a diverse group of proteins which can recognize different types of carbohydrates specifically and reversibly. Though first characterized in plants, lectins have now been identified in all other forms of life. ... -
Structure Analysis Of Plant Lectin Domains
(2014-04-07)Lectins are multivalent carbohydrate binding proteins that specifically recognise diverse sugar structures and mediate a variety of biological processes, such as cell-cell and host-pathogen interactions, serum glycoprotein ...