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Now showing items 917-936 of 6421
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Decentralized information flow control for the robot operating system
The Robot Operating System (ROS) is a popular open-source middleware widely used in the robotics community. While ROS provides extensive support for robotic application develop- ment, it lacks certain fundamental security ... -
Decentralized Sustainable Energy Planning For Tumkur District, India
(2010-02-18)The energy-planning involves finding a set of sources and conversion devices so as to meet the energy requirements/demands of all the activities in an optimal manner. This could occur at centralized or decentralized level. ... -
Deciphering Functions & Interactions of Fission Yeast Splicing Factor SpSlu7 Relevant to Constitutive & Alternative Splicing
The fission yeast genome with abundant multi-intronic transcripts, degenerate splice signals and presence of alternative splicing machinery is an attractive unicellular fungal model to investigate splice-site recognition ... -
Deciphering Structure-Function Relationships in a Two-Subunit-Type GMP Synthetase by Solution NMR Spectroscopy
(2018-04-24)The guanosine monophosphate synthetase (GMPS) is a class I glutamine amidotransferase, involved in the de-novo purine nucleotide biosynthesis. The enzyme catalyzes the biochemical transformation of xantosine (XMP) into ... -
Deciphering the biochemical and biophysical properties of the Holliday junction resolvases RuvC and RuvX from Mycobacterium smegmatis
Homologous recombination (HR) is a ubiquitous cellular process that occurs in all three domains of life as well as in DNA and RNA viruses. In eukaryotes, HR is critically important for homology-directed DNA repair (HDDR) ... -
Deciphering the evolutionary significance of maintaining cryptic genetic systems by bacteria
Cryptic genes are phenotypically silent DNA sequences with the potential to code for a function, but remain inactive during the normal life span of the organism. However they can be activated by a single mutational event ... -
Deciphering the genetic regulators of cuticle barrier function and longevity in Caenorhabditis elegans
Ever since Sydney Brenner introduced Caenorhabditis elegans in the early 60s as a model system, this worm has contributed to many ground-breaking discoveries in science. It has served as an excellent model to study animal ... -
Deciphering the mechanisms employed by Salmonella to mediate modulation of host endo-lysosomal machinery
Salmonella genus encompasses Gram-negative, rod-shaped, facultative anaerobic, non-sporulating, and predominantly motile enteric bacteria. It causes pathogenesis in a wide array of hosts, from cold-blooded animals to humans ... -
Deciphering the Mechanisms of AMPK Activation upon Anchorage- Deprivation
(2018-01-07)AMP-activated protein kinase (AMPK) is a key regulator of energy homeostasis in cells. It has been implicated as a therapeutic target for various metabolic diseases like type II diabetes and obesity. However, its role in ... -
Deciphering the role of host protein HuR in RNA virus life cycle and pathogenesis: Hepatitis C Virus and SARS-CoV-2 as exemplars.
Viruses pose a major threat to human health and the ongoing SARS-CoV-2 pandemic proves as the best evidence for that. Historically, RNA viruses have a major potential to cause such pandemics. They utilise RNA binding ... -
Deciphering the Role of METTL3-Dependent m6A-epitranscriptome in Glioma Stem-like Cells
The major roadblocks in treatment for GBM are resistance to therapy and recurrence of GBM cells. Regardless of various treatment strategies, the average survival of GBM patients is poor and incidence of recurrence remains ... -
Deciphering the role of outer membrane porins in the pathogenesis of Salmonella enterica serovar Typhimurium
Porins are highly conserved barrel-shaped proteins bound to the bacterial outer membrane and involved in the selective transport of charged molecules across the membrane. They consist of parallel and anti-parallel β sheets ... -
Decision Making under Uncertainty : Reinforcement Learning Algorithms and Applications in Cloud Computing, Crowdsourcing and Predictive Analytics
In this thesis, we study both theoretical and practical aspects of decision making, with a focus on reinforcement learning based methods. Reinforcement learning (RL) is a form of semi-supervised learning in which the agent ... -
Decoding Epigenetic Regulators in Cancer: Acetylation of HIF2A by Histone Acetyltransferase 1 (HAT1) is essential for executing hypoxia response in glioma
Gliomas are tumors of the central nervous system arising from glial cells. Based on the origin of the cell type, it can be astrocytoma, oligodendroglioma, and ependymoma. Astrocytoma is the most common type of glioma, ... -
Decoding of Attention and Behavioral State Using Local Field Potentials
Visual attention has been shown to modulate perceptual behavior and neuronal activity. Early psychophysical studies on attention showed that the subjects detected a target presented at the attended location better (i.e., ... -
Decomposition of the tensor product of Hilbert modules via the jet construction and weakly homogeneous operators
Let ½ Cm be a bounded domain and K :£!C be a sesqui-analytic function. We show that if ®,¯ È 0 be such that the functions K® and K¯, defined on £, are non-negative definite kernels, then theMm(C) valued function ... -
Deep Convolutional and Generative Networks for Ocean Synoptic Feature Extraction and Super Resolution from Remotely Sensed Images
Accurate extraction of Synoptic Ocean Features and Downscaling of Ocean Features is crucial for climate studies and the operational forecasting of ocean systems. With the advancement of space and sensor technologies, the ... -
Deep Learning Based Channel Estimation in Wireless Communications
Deep learning techniques which employ trained neural networks to solve problems have witnessed widespread adoption in diverse fields like medicine, architecture, robotics, autonomous vehicles, wireless communications, ...