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Crystal Structures of Native and AdoMet Bound rRNA Methyltransferase from Sinorhizobium meliloti : Structural Insights into rRNA Recognition. Evolutionary, Structural and Functional Studies on Nucleoid-Associated Proteins HU and IHF
DNA- and RNA-binding proteins play a central role in gene regulation, which includes transcriptional control, alternative splicing, post-translational and transcriptional modifications like methylation and acetylation among ... -
Crystal Structures Of Native And Xylosaccharides-Bound Alkali Thermostable Xylanase From An Alkalophilic Bacillus SP. NG-27: Structural Insights Into Alkalophilicity. Analysis Of C-H...O Hydrogen Bonds In Helices Of Globular Proteins
(2007-11-21)Xylanases are xylan-degrading enzymes, belong to glycosyl hydrolases (GH). Xylanases from the two major families 10 (GH10) and 11 (GH11) catalyze the hydrolysis of internal β-, bonds of xylan backbone. Xylan is the second ... -
Crystal Structures of Sortase A from Streptococcus Penumoniae : Insights into Domain-Swapped Dimerization. Crystal Structures of Designed Peptides : Inhibitors of Human Islet Amyloid Polypeptide (hIAPP) Fibrillization Implicated in Type 2 Diabetes And Those Forming Self-Assembled Nanotubes
(2017-09-27)Sortases are cell-membrane associated cysteine transpeptidases that are essential for the assembly and covalent anchoring of certain surface proteins to the cell wall in Gram-positive bacteria. Thus, they play critical ... -
Crystalline Silicon Carbide Thin Films for Ultraviolet Detection
UV light detection has a lot of applications including secured satellite communication, solar and celestial observation and biological imaging. Wide bandgap materials are used to sense UV light. SiC is an excellent material ... -
Crystallization and Preliminary Structural Studies on Mycobacterium tuberculosis RuvX
The deadly pathogen Mycobacterium tuberculosis has been characterized for its virulence in immense detail. Regardless of this, the capability of M. tuberculosis to combat extreme stress conditions inside the host cell for ... -
Crystallographic and analytical ultracentrifugation studies of the E. coli acetohydroxy acid synthase I enzyme
This thesis ellucidates the mechanism of activation and regulation of AHAS I enzyme from Escherichia coli that was characterised using crystallographic and sedimentation velocity analytical ultracentrifugation studies. AHAS ... -
Current-Mode Techniques In The Synthesis And Applications Of Analog And Multi-Valued Logic In Mixed Signal Design
(2008-10-07)The development of modern integration technologies is normally driven by the needs of digital CMOS circuit design. Rapid progress in silicon VLSI technologies has made it possible to implement multi-function and high ... -
Curvature Calculations Of The Operators In Cowen-Douglas Class
(2014-03-03)In a foundational paper “Operators Possesing an Open Set of Eigenvalues” written several decades ago, Cowen and Douglas showed that an operator T on a Hilbert space ‘H possessing an open set Ω C of eigenvalues determines ... -
Cyclic AMP In Mycobacteria Adenylyl Cyclases And Cyclic AMP Receptor Proteins
(2013-01-28)The discovery of cyclic AMP (cAMP), nearly 50 years ago by Sutherland radically altered the appreciation of metabolic regulation. Since then the presence of cAMP and its tremendous physiological impact has been demonstrated ... -
Cyclic AMP-Regulated Protein Lysine Acetylation In Mycobacteria
(2015-07-17)Tuberculosis continues to be one of the major causes of morbidity and mortality worldwide. Several mycobacterial species such as M. tuberculosis and M. africanum are responsible for causing this disease in humans. Reports ... -
Cyclic Pursuit : Variants and Applications
(2018-02-11)The classical n-bugs problem has attracted considerable attention from researchers. This problem stems from the study of movement of a group of animals. In the context of multi- agent systems the problem has been modelled ... -
Cylindrical Fretting And Delamination : Axisymmetric Static And Dynamic Analysis
(2011-01-17)Axisymmetric analysis of cylindrical contacts is considered in the context of axisymmetric assemblies such as shrink-fits. Fretting fatigue induces sub-critical cracks along the contact interface of press fits especially ... -
Cytosolic Lysophosphatidic Acid Acyltransferase : Implications in Lipid Biosynthesis in Yeast, Plants and Human
(2018-02-11)Cytosolic LPA acyltransferase in yeast An isooctane tolerant strain of S. cerevisiae KK-12 was reported to have increased saturated fatty acid content (Miura et. al., 2000). Amongst the various genes upregulated on isooctane ... -
Cytotoxic T lymphocyte Responses Against Japanese Encephalitis Virus In Mice: Specificity And Immunotherapeutic Value
(Indian Institute of Science, 2005-10-07)Cytotoxic T Lymphocytes (CTL) are known to play an important role in clearing infectious virus from infected hosts in a variety of viral infections. Depending on the type of virus and mode of virus entry both class I and ... -
Cytotoxicity of Metal Based Anticancer Active Complexes and their Targeted Delivery using Nanoparticles
(2018-02-21)Use of metal based anticancer medication began with the clinical approval of cisplatin in 1978. Research led to the development of six platinum based drug candidates which are in use around the world. However there is a ... -
Damping of magnetic-Coriolis waves with imposed magnetic field orthogonal to the axis of rotation
Small-scale columnar structures (<10 km radius) in Earth's outer core result from inertial waves. In highly conducting fluid, magnetic field behaviour resembles stretched elastic strings and transmits disturbances as Alfvén ...