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Now showing items 6222-6241 of 6421
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Understanding quantitative process physics of 3D binderjet printing with validation in Ti-6Al-4V and inkjet bioprinting of mammalian cells
In the field of additive manufacturing, laser or electron beam based 3D printing is widely investigated for biomedical applications. However, much less explored is the binderjet 3D printing, which allows processing of ... -
Understanding Rules of Assembly and Species Interactions in Mixed-species Bird Flocks
In mixed-species bird flocks (flocks hereafter), participants vary in their degree of similarity with each other. Flock participants can gain group size (supplementary) benefits by choosing similar flock partners, or ... -
Understanding Solvent Effect On Triplet State Structure Of Thioxanthone And Its Derivatives Using Time-Resolved Resonance Raman Spectroscopy
(2014-05-01)It has long been recognized that course and efficiency of a chemical reaction is largely mediated by the short-lived transient species (excited state or radicals) which are formed as reactive intermediates during a chemical ... -
Understanding spontaneous emission in the strong coupling regime of an emitter and absorbing matter
This thesis proposes a partition of optical states into radiative and non-radiative parts when an emitter is proximal to resonant absorbing nanostructures. The conventional partition is valid only for the weak coupling ... -
Understanding Structure And Growth Of Physisorbed Films : A Combined Atomic Force Microscopy And Modeling Study
(2014-10-16)Surface modification has wide ranging implications in lubrication, microelectromechanical systems (MEMS), colloidal systems and biological membranes. Surface modification plays an important role in stabilizing gold ... -
Understanding structure, function, and dynamics in macromolecular complexes
In the scope of my thesis work, a concerted effort was undertaken to elucidate bi- ological functions through the lens of structural analysis, employing protein dy- namics. The role of protein dynamics in shaping and ... -
Understanding the adaptive responses of Salmonella Typhimurium during bile stress
Salmonella Typhimurium (S. Typhimurium) is an enteric pathogen that causes gastroenteritis. Although gastroenteritis is usually non-life threatening in healthy adults, it can cause fatality in children and immunocompromised ... -
Understanding the architecture of mitochondrial presequence translocase machinery and its implications in ALS progression
The current thesis describes the structural organization of the presequence translocase machinery and its functional association with ALS pathogenesis. The TIM23 complex is essential for the mitochondrial biogenesis of ... -
Understanding the Behavior of the Sun's Large Scale Magnetic Field and Its Relation with the Meridional Flow
(2018-07-05)Our Sun is a variable star. The magnetic fields in the Sun play an important role for the existence of a wide variety of phenomena on the Sun. Among those, sunspots are the slowly evolving features of the Sun but solar ... -
Understanding the Biology of Heat Shock Protein 90 in Opportunistic Fungal Pathogens
Heat shock protein 90 is one of the most abundant and evolutionary conserved class of molecular chaperones present throughout the biological kingdom. It is a specialist chaperone as its function extends beyond protein ... -
Understanding the demixing behavior and structure-property correlation in graphene oxide containing LCST blends
A number of researchers have studied about the effects of different nanoparticles on the phase separation of LCST polymer blend systems. Many nanoparticles such as carbon nanotubes and silica have been incorporated in ... -
Understanding the Dynamic Organization of the Presequence-Translocase in Translocation of Preproteins Across Mitochondrial Inner Membrane
(2018-05-08)Mitochondrion is an endosymbiotic organelle synthesizing ~1% of its proteome, while remaining ~99% of the proteins are encoded by the nuclear genome and translated on the cytosolic ribosome. Therefore active mitochondrial ... -
Understanding the dynamics and evolution of cratons
The earth is the only rocky planet in the solar system that exhibits plate tectonics. One of the basic tenets of plate-tectonics is that it recycles the lithosphere within a few hundred million years. No oceanic lithosphere, ... -
Understanding the Functions of Nucleoid Associated Proteins in Mycobacterium tuberculosis
The prokaryotic genome, though lacks a membrane bound organelle for its housing, is restricted to only about 25% of the cytoplasmic space called the nucleoid. The dramatic compaction required for the genome to fit in is ... -
Understanding The Growth And Properties Of Functional Inorganic Nanostructures : An Interfacial Approach
(2010-07-23)Surfaces and interfaces are of fundamental importance from the nucleation to growth of crystals formed under different conditions such as vapor phase, liquid phase including biomineralisation conditions. Recently there is ... -
Understanding the Heat Shock Response Pathway in Plasmodium Falciparum and Identification of a Novel Exported Heat Shock Protein
(2018-02-27)Infections or diseases are not just stressful for the one who encounters it. The pathogens causing the same also have to deal with the hostile environment present in the host. The maintenance of physiological homeostatic ... -
Understanding the influence of electric field and dual doping on cytocompatibility of calcium phosphate bioceramics: Experimental and computational study
Although doped bioceramics have been widely investigated for biomedical applications, the co-doped bioceramics remain mostly unexplored for bone regeneration and dental applications. Given this background, we have successfully ... -
Understanding the interaction mechanism of bacterial virulence factors and effector proteins with host lipid membrane using single particle cryo-electron microscopy
Pathogenic bacteria employ an array of biological macromolecules and cellular structures that help in the initiation and progression of disease in host organism. These ‘virulence factors’ can either be secreted by the ... -
Understanding the interplay between immune response and virus evolution
RNA viruses are the underlying cause of many human diseases, including the common cold, influenza, dengue fever, and COVID-19. Their ability to evolve rapidly makes them challenging to tackle, resulting in public health ... -
Understanding the Long-term Impact and Mechanism of Action of Endosulfan, an Organochlorine Pesticide on Fertility, Development and Growth of Mice
Endosulfan (ES) is one of the major broad-spectrum organochlorine pesticides categorized as Class II (moderately hazardous) by WHO and Class I (highly acutely toxic) by US Environment Protection Agency. Although the use ...