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Now showing items 5224-5243 of 6421
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Structural Studies on Mycobacterium Tuberculosis Peptidyl-tRNA Hydrolase and Ribosome Recycling Factor, Two Proteins Involved in Translation
(2017-11-27)Protein synthesis is a process by which organisms manufacture their proteins that perform various cellular activities either alone or in combination with other similar or different molecules. In eubacteria, protein synthesis ... -
Structural Studies on Non-toxic Homologues of type II Ribosome Inactivating Proteins (RIPs)
This thesis is concerned with structural and related studies on two non-toxic homologues of type II RIPs. Type II RIPs, which are more toxic than type I, contain an additional lectin chain (B-chain) covalently linked to ... -
Structural Studies On Physalis Mottle Virus Capsid Proteins & Stress Response Proteins Of Oryza Sativa And Salmonella Typhimurium
(2013-04-26)X-ray crystallography is one of the most powerful tools for the elucidation of the structure of biological macromolecules such as proteins and viruses. Crystallographic techniques are extensively used for investigations ... -
Structural Studies On Pyridoxal 5'-Phosphate Dependent Enzymes Involved In D-Amino Acid Metabolism And Acid Tolerance Reponse
(2015-08-19)Metabolism of D-amino acids is of considerable interest due to their key importance in cellular functions. The enzymes D-serine dehydratase (DSD) and D-cysteine desulfhydrase (DCyD) are involved in the degradation of D-Ser ... -
Structural Studies on SeMV Chimeras and TSV : Insights into Capsid Assembly
(2018-05-23)Assembly of virus capsid protein (CP) into icosahedrally symmetric particles is an intriguing and elegant process. In most cases of virus assembly, a large number of identical protein subunits self-assemble to generate a ... -
Structural Studies on Sesbania Mosaic Virus Protease Domain and Plasmodium Falciparum Hypoxanthine Quanine Phosphoribosyl Transferase and Triosephosphate Isomerase
X-ray crystallography is a powerful tool to obtain atomic resolution details on the three-dimensional structure of biological macromolecules. Crystallographic techniques find wide applications in understanding macromolecular ... -
Structural Studies On The Enzymes FabI And FabZ Of Plasmodium Falciparum
(2008-10-20)The thesis deals with X-ray crystallographic analysis of two enzymes involved in the fatty acid biosynthesis pathway, known as Fatty Acid Synthase or FAS, of the malarial parasite, Plasmodium falciparum, in order to ... -
Structural Studies on the Intracellular Steps that Govern the Staphylococcus aureus Quorum Sensing System.
Quorum sensing in bacteria has been extensively examined over the past two decades. These studies suggest that the molecular mechanism that governs quorum sensing incorporates niche-specific, environmentally sensitive ... -
Structural Studies on the Role of Hinge involved in Domain Swapping in Salmonella Typhimurium Stationary Phase Survival Protein (SurE) and Sesbania Mosaic Virus Coat Protein
(2018-05-09)A unique mechanism of protein oligomerization is domain swapping. It is a feature found in some proteins wherein a dimer or a higher oligomer is formed by the exchange of identical structural segments between protomers. ... -
Structural Studies On The Rotaviral Enterotoxin NSP4
(2013-02-12) -
Structural Studies on Thiolases and Thiolase-like Proteins
(2017-11-21)The genus Mycobacterium comprises some of the most devastating pathogens that infect humans. Mycobacterium tuberculosis causes tuberculosis in humans leading to high morbidity and mortality. The disease is especially ... -
Structural Studies On Three Pyridoxal-5'-Phosphate Dependent Enzymes : N-Acetylornithine Aminotransferase, Serine Hydroxymethyltransferase And Diaminopropionate Ammonia Lyase
(2009-09-02)Pyridoxal 5’-phosphate (PLP), the active form of vitamin B6, is a cofactor for many enzymes involved in the metabolism of amino acids, amino acid derived metabolites and some amino sugars. PLP is one of the most versatile ... -
Structural Studies On Three-Fold Symmetric Plant Lectins
(2013-05-21)Lectins, multivalent carbohydrate-binding proteins of non-immune origin, have the unique ability to decode the information contained in complex carbohydrate structures of glycoproteins and glycolipids by stereo-specifically ... -
Structural Studies on Thymidylate Kinase : Evolution, Specificity and Catalysis
(2018-05-30)Thymidylate kinase (TMK) is a key enzyme for DNA synthesis. It occurs at the junction of the de novo and salvage pathways for the synthesis of deoxythymidine triphosphate (dTTP). Its inhibition affects cell viability, ... -
Structural Studies On Winged Bean Agglutinins
(Indian Institute of Science, 2007-01-11)Lectins are multivalent carbohydrate binding proteins that specifically recognise diverse sugar structures and mediate a variety of biological processes, such as cell-cell and host-pathogen interactions, serum glycoprotein ... -
Structural, Biophysical And Biochemical Studies On Mannose-Specific Lectins
(2013-01-17)For a long time, the scientific community underestimated the value of carbohydrates and the approach of most scientists to the complex world of glycans was apprehensive. The scenario, however, has changed today. With the ... -
Structural, Electronic And Vibrational Properties Of n-layer Graphene With And Without Doping : A Theoretical Study
(2011-07-11)Graphene – a two-dimensional honeycomb lattice of sp2-bonded carbon atoms – has been attracting a great deal of research interest since its first experimental realization in 2004, due to its various novel properties and ... -
Structural, Ferroelectric, Piezoelectric and Phase Transition Studies of Lead Free (Na0.5Bi0.5)TiO3 Based Ceramics
(2018-04-23)Ferroelectric materials, especially the polycrystalline ceramics, are very promising material for a variety of applications such as high permittivity dielectrics, ferroelectric memories, piezoelectric sensors, piezoelect ... -
Structural, Functional And Transcriptional Analysis Of Nucleoside Diphosphate Kinase From Mycobacterium Smegmatis mc2 155
(2011-08-05)Maintenance of the levels of nucleoside triphosphates (NTPs) as well as their corresponding deoxy derivatives (dNTPs) is crucial to all growth and developmental processes. The enzyme nucleoside diphosphate kinase (NDK) ... -
Structural, Magnetic and Electrical Studies of Multiferroic BiFeO3 and CuO Epitaxial Thin Films
The multiferroics are an important class of multifunctional material which simultaneously possess spontaneous ferroelectric polarization and magnetic ordering. If there exists a coupling between the ferroelectricity and ...