Browsing by Title
Now showing items 3498-3517 of 6421
-
Molecular Characterization of Groundnut Bud Necrosis Virus Encoded Non Structural Protein m (NSm)
(2018-01-28)Chapter 3 Groundnut Bud Necrosis Virus (GBNV) is a tripartite ambisense RNA plant virus that belongs to serogroup IV of Tospovirus genus. Non-Structural protein-m (NSm), which functions as movement protein in tospoviruses, ... -
Molecular Characterization of Mannose Binding Lectins
Lectins are proteins of non-immunologic origin that bind to carbohydrates with high fidelity. They constitute a large class of multivalent recognition molecules that specifically interact with their cognate sugar moieties ... -
Molecular Characterization Of The SLC22A18AS Gene From The Imprinted Human Chromosome Segment 11p15.5
(2011-02-21)The imprinting status of the SLC22A18AS gene, located in the human chromosome segment 11p15.5, was studied using PCR-SSCP analysis and fetal tissues from a battery of 17 abortuses. This gene showed monoallelic expression ... -
Molecular Cloning And Characterization Of A Calcium-Depdendent Protein Kinase Isoform ScCPK1 From Swainsona Canescens
(2013-06-10)Plants are constantly exposed to pathogens and various environmental stresses, such as cold, salinity and drought. Plants normally respond rapidly to these biotic and abiotic stresses. Efficient perception of biotic and ... -
Molecular Construction Using Carbene and Diboron Systems: Catalytic Transformation of C-C and C-Hetero Atom Bonds
The thesis presents an unconventional approach for the molecular construction using carbenes as the carbon source, and water as the hydrogen source. A gold-catalyst has been used to transfer the carbenes to effect ... -
Molecular Determinants of Mutant Phenotypes in the CcdAB Toxin -Antitoxin System
(2018-05-29)A major challenge in biology is to understand and predict the effect of mutations on protein structure, stability and function. Chapter 1 provides a general introduction on protein sequence-structure relationships and use ... -
Molecular determinants of self-assembly of the pore forming toxin Cytolysin A
Pore forming toxins (PFTs) belong to a class of bacterial exotoxins that disrupt the biological membrane barrier by formation of nanopores. These toxins are central to the virulence of pathogens such as S. pneumoniae, ... -
Molecular Dynamics Investigations of Hybrid Nanopores for Single Molecule DNA Sequencing
High throughput methods accelerate the drug discovery, biomolecule detection and sequencing applications pipeline. Single molecule detection technique facilitates the implementation of high throughput methods by eliminating ... -
Molecular dynamics investigations of the bacterial cell envelope: Elucidating differential barriers for antimicrobials
The bacterial cell envelopes possess a complex multilayered architecture exhibiting unique properties evolved to regulate interactions with the external environment and molecules with antimicrobial properties. A molecular ... -
Molecular Dynamics simulations reveal the role of membrane cholesterol in the pore forming pathway of Cytolysin A
We investigate the interactions of pore-forming toxins (PFTs) with cholesterol-rich membranes through atomistic molecular dynamics simulations. The PFT of interest is Cytolysin A (ClyA or HlyE). Cytolysin A (ClyA), an ... -
Molecular Dynamics Studies of Diffusion in Confined Regions
Diffusion of guest molecules under confinement of zeolites shows many interesting properties due to guest-host interactions. This thesis explores some of these interesting behaviours relating to the diffusion of guest ... -
Molecular Ecology of the Primitively Eusocial Wasp Ropalidia Marginata : Relatedness, Queen Succession and Population Genetics
(2018-06-08)Altruism is defined as a trait in an individual that increases some other individual’s fitness at the expense of her own. Therefore, existence of such traits in a population is an evolutionary paradox, as natural selection ... -
Molecular Expression Through Fluorescence: Studies In Probe Design And Aggregation
(2007-12-29)The present thesis entitled, "Molecular expression through fluorescence: Studies in probe design and aggregation" describes very simple bi-functional donor-acceptor poly-aromatic fluorophores that have been shown to possess ... -
Molecular Genetic Analysis Of Flower Development In Rice
(2011-12-12) -
Molecular Genetic Analysis Of The Role Of Nse2, A SUMO E3 Ligase Of The Smc5/6 Complex, In Resisting Genotoxic Stress And Maintaining Chromosome Stability In Saccharomyces Cerevisiae
(2011-01-20)DNA repair pathways have evolved to protect the genome from damage caused by intrinsic and extrinsic factors. Although numerous DNA repair mechanisms have been studied and reported, information regarding how they coordinate ... -
MOLECULAR GENETIC ANALYSIS OF THE TUBEROUS SCLEROSIS COMPLEX
(Indian Institute of Science, 2005-02-21)Tuberous sclerosis complex (TSC) is an autosomal dominant disorder that affects several organs in the human body including the brain, heart, kidneys, eyes, skin, spleen, liver and lungs [Roach, et al., 1999]. TSC is ...