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Improving Glioblastoma Management: A Study of Biomarkers, Tumor Microenvironment and Chemoresistance
Glioblastoma (GBM) is an aggressive form of adult brain tumors. The current standard of care includes maximal safe resection followed by concurrent chemo-radiation therapy and adjuvant chemotherapy with temozolomide. ... -
Improving Healing Outcomes in Diabetic Wounds by Understanding and Modulating Immune Responses
Diabetic Foot Ulcers (DFUs) are chronic wounds that show delayed or absence of healing in individuals with diabetes. Currently, diabetic wounds are managed clinically through regular debridement, pressure off-loading, ... -
Improving High Temperature Strength of 2219 Al Alloy by Minor Alloying Additions
(2018-06-25)Among Al alloys, 2219 Al alloy possesses highest strength at elevated temperatures. However, the application of this alloy is also restricted to a maximum temperature of 150°C, above which, the strengthening precipitates ... -
Improving hp-Variational Physics-Informed Neural Networks: A Tensor-driven Framework for Complex Geometries, and Singularly Perturbed and Fluid Flow Problems
Scientific machine learning (SciML) combines traditional computational science and physical modeling with data-driven deep learning techniques to solve complex problems. It generally involves incorporating physical ... -
Improving Last-Level Cache Performance in Single and Multi-Core Processsors
(2018-04-23)With off-chip memory access taking 100's of processor cycles, getting data to the processor in a timely fashion remains one of the key performance bottlenecks in current systems. With increasing core counts, this problem ... -
Improving Mechanical Properties and Self-Healing by Dynamic Bonds at Interface in Carbon Fiber Reinforced Epoxy Laminate and its Recycling
Carbon fiber-reinforced epoxy (CFRE) laminates have revolutionized aerospace engineering due to their exceptional strength-to-weight ratio, corrosion resistance, and design flexibility. However, challenges such as weak ... -
Improving photoacoustic imaging with model compensating and deep learning methods
Photoacoustic imaging is a hybrid biomedical imaging technique combining optical ab- sorption contrast with ultrasonic resolution. It is a non-invasive technique that is scalable to reveal structural, functional, and ... -
Improving quality of speech in VoIP using time-scale modification
Voice over Internet Protocol (VoIP) is an emerging technology that enables the transport of voice over the Internet. The quality of delivered voice is a critical issue due to packet loss and end-to-end delay variations ... -
Improving quality of speech in VoIP using time-scale modification
Voice over Internet Protocol (VoIP) is an emerging technology that enables the transport of voice over the Internet. The quality of delivered voice is a critical issue due to packet loss and end-to-end delay variations ... -
Improving The Communication Performance Of I/O Intensive And Communication Intensive Application In Cluster Computer Systems
(2009-04-13)Cluster computer systems assembled from commodity off-the-shelf components have emerged as a viable and cost-effective alternative to high-end custom parallel computer systems.In this thesis, we investigate how scalable ... -
Improving the Precision of a Scalable Demand-Driven Null- Dereference Verification for Java
(2018-03-19)The problem addressed in this thesis is sound, scalable, demand-driven null-dereference verification for Java programs via over-approximated weakest preconditions analysis. The base version of this analysis having been ... -
In Silico Perspectives on RNA Structures Modulating Viral Gene Expression and Mechanics of tRNA Transport
(2018-07-19)The repertoire of cellular functions mediated by Ribonucleic acid (RNA) molecules have expanded considerably during the last two decades. The role played by RNA in controlling and regulating gene expression in ... -
In situ analysis of large strain deformation in tool-workpiece contacts
Large strain plastic deformation is central to manufacturing operations like metal cutting, rolling, and extrusion. Standard approaches for describing and understanding this deformation, such as analytical methods, numerical ... -
In Situ Crystallography And Charge Density Analysis Of Phase Transitions In Complex Inorganic Sulfates
(2013-10-03)The thesis entitled “In situ crystallography and charge density analysis of phase transitions in complex inorganic sulfates” consists of six chapters. Structural changes exhibited by ferroic and conducting materials are ... -
In Situ Transmission Elecron Microscope Triboprobe For Tribological Studies Of Materials At Nanoscale
(2013-09-10)In most of the tribological experiments studying friction and wear behaviour, the contact interface is hidden. The present work attempts to overcome this hidden-interface problem by carrying out real-time tribological ... -
In vivo and in vitri biotransformation of terpenoids in rats
Terpenoids are ubiquitous in nature and living systems are exposed to these compounds. Although the metabolism of these compounds in mammals has been studied since the beginning of the century, the exhaustive investigation ... -
In vivo mechanistic insights into the trans-splicing based expression of Hsp90 in Giardia lamblia
Giardia lamblia, a simple yet intriguing protozoan parasite, challenges conventional paradigms in gene expression through its unique mechanism of trans-splicing for Heat Shock Protein 90 (Hsp90). As a primitive organism, ... -
In-Cylinder Experimental and Modeling Studies on Producer Gas Fuelled Operation of Spark Iginited Gas Engines
(2018-08-10)The current work, through experimental and numerical investigations, analyses the process and cycle level deviations in engine response on fuelling multi-cylinder natural gas engines with producer gas. Producer gas is a ...