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Mechanics of collective cell migration on substrates of different stiffness
Collective cell migration is characteristic in many physiological processes such as wound closure, morphogenesis, and cancer tumour metastasis. Experiments on cell monolayers demonstrated the formation of finger-like ... -
Mechanics of cutting in granular media
Cutting is an important deformation process encountered during many instances in the engineering of infrastructure, such as trawling, trenching, and excavation. This thesis presents the results of an experimental program ... -
Mechanics of Drilling in Porous Brittle Solids
(2018-01-01)This thesis presents a detailed experimental programme on understanding the mechanics of drilling in porous brittle solids. Gypsum was used as a model material for this experimental study, in which the mechanics of drilling ... -
Mechanics of Martensitic Phase transformation in shape memory alloys Experiments and modelling
Thermally activated NiTi based Shape Memory Alloys (SMAs) are of tremendous practical interest as actuators in varied engineering applications owing to its characteristic Martensitic Phase Transformation (MPT). The MPT in ... -
Mechanising knot Theory
(2018-01-31)Mechanisation of Mathematics refers to use of computers to generate or check proofs in Mathematics. It involves translation of relevant mathematical theories from one system of logic to another, to render these theories ... -
Mechanism And Control Of Sulphuric Acid Induced Heave in Soils
(2010-07-12)The escalating pollution of the environment has been one of the greatest concerns of science in recent years. Industrial advances in agriculture, expansion of chemical industries and a general change in lifestyle all over ... -
Mechanism and Modeling of Contact Damage in ZrN-Zr and TiAIN-TiN Multilayer Hard Coatings
(2018-02-23)With the amalgamation of hard coating in cutting tools industries for three decades now, a stage with proven performance has been reached. Today, nearly 40% of all cutting tools used in machining applications are sheltered ... -
A Mechanism Design Approach To Resource Procurement In Computational Grids With Rational Resource Providers
(2009-07-08)A computational grid is a hardware and software infrastructure that provides dependable, consistent, pervasive, and inexpensive access to high-end computational capabilities. In the presence of grid users who are autonomous, ... -
Mechanism Design For Strategic Crowdsourcing
(Indian Institute of Science, 2013-12-17)This thesis looks into the economics of crowdsourcing using game theoretic modeling. The art of aggregating information and expertise from a diverse population has been in practice since a long time. The Internet and the ... -
Mechanism of Abrin-Induced Apoptosis and Insights into the Neutralizing Activity of mAb D6F10
(2017-11-23)Abrin is a potent toxin obtained from the seeds of Abrus precatorius. It is a heterodimeric glycoprotein consisting of an A and a B subunit linked together by a disulfide bond. The toxicity of the protein comes from the A ... -
Mechanism Of Activation Of Bacteriophage Mu Late Genes By Transcription Activator Protein C
(2013-01-24)Initiation of transcription is a major step in the regulation of gene expression. A dominant theme in regulation of gene expression lies in understanding the mechanism involved in selective expression of the genes in ... -
Mechanism Of Anticancer And Antimalarial Action Of A Modulator Of Heat Shock Proteins
(2007-11-16)This thesis entitled “Mechanism of Anticancer and Antimalarial Action of a Modulator of Heat Shock Proteins” describes the successful elucidation of the mechanism of anticancer and antimalarial action of 15-Deoxyspergualin ... -
The Mechanism Of Fragility Of The BCL2 And HOX11 Breakpoint Regions During t(14;18) And t(10;14) Chromosomal Translocations In Lymphoid Cancers
(2014-08-05)Haematological cancers like leukemia and lymphoma are characterized by genetic abnormalities, specifically chromosomal translocations. Analyses of the translocation breakpoint regions in patients have shown that some loci ... -
Mechanism Of Interaction Of Escherichia Coli σ70 With Anti-Sigma Factors
(2009-08-03)In bacteria, the RNA polymerase (RNAP) consists of the following subunits: α2, β, β’, ω and σ. The core RNAP (α2ββ’ω) possesses the polymerising activity and it associates with one of the sigma factors to initiate transcription ... -
Mechanism Of mom Gene Transactivation By Transcription Factor C Of Phage MU
(Indian Institute of Science, 2007-04-26)Regulation of transcription initiation is the major determining event employed by the cell to control gene expression and subsequent cellular processes. The weak promoters, with low basal transcription activities, are ... -
Mechanism Of RAG Action As A Structure-Specific Nuclease : Implications In Genomic Instability In Lymphoid Cells
(2013-07-18)Recombination Activating Genes (RAGs) orchestrate the process called V (D) J recombination, which enables the vertebrate adaptive immune system to specifically recognize millions of antigens. During this recombination ... -
Mechanism of RAG Regulation During Its Physiological and Pathological Functions in Lymphoid Cells
(2018-08-11)RAGs (Recombination Activating Genes) are responsible for generation of antigen receptor diversity in case of B-cells and T-cells, through the process of combinatorial joining of different V (variable), D (diversity) and ... -
Mechanism of Recycling of Ribosomes Stalled on mRNAs in Escherichia Coli
(2018-07-28)Studies reported in this thesis address the question of how pre-termination ribosomal complexes stalled during translation of mRNA are recycled. The process of recycling of the stalled ribosomes involves many translational ... -
Mechanism Of Replication Of Sesbania Mosaic Virus (SeMV)
(2015-08-12)