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Investigating Instability Mitigation through Flame Oscillator Synchronization
Stringent emission regulations for reducing NOx and soot emissions are driving gas turbine combustors manufacturers to adopt lean premixed combustion technology. However, the rich dynamics of turbulent, lean premixed ... -
Investigating Mechanical Properties of Suspended Ovarian Cancer Cells and Clusters
The peritoneal cavity of a patient suffering from advanced epithelial ovarian cancer is filled with disseminated multicellular aggregates, commonly known as spheroids. These spheroids colonize abdominal organs leading to ... -
Investigating mechanisms underlying astrocytic involvement in depressive-like behavior and antidepressant action
Major Depressive disorder (MDD) is a complex, multifactorial psychiatric illness which affects over 20% of the population worldwide. Despite its prevalence, our understanding of its pathophysiology is severely limited, ... -
Investigating Membrane Dynamics And Oligomerization Of Pore-forming Toxins Using Single-molecule Fluorescence Techniques
The biological membrane is a thin fluidic matrix composed of a lipid bilayer that forms the primary cellular barrier against the extracellular environment. The high-density of embedded proteins and glycosylated molecules ... -
Investigating Neural Mechanisms of Word Learning and Speech Perception
Language learning and speech perception are remarkable feats performed by the human brain, involving complex neural mechanisms that allow us to understand and communicate with one another. Unravelling the mysteries of these ... -
Investigating Ocular and EEG parameters for pilot’s cognitive load estimation using flight simulators
Present day aircraft systems are becoming incredibly complicated with the advent of new technologies. As per International civil aviation organization’s safety report, failure of mechanical or any physical hardware has ... -
Investigating Partners of OsMADS1 Transcription Factor and functions for some associated factors for roles in rice inflorescence and floral development
Title: Investigating Partners of OsMADS1 Transcription Factor and functions for some associated factors for roles in rice inflorescence and floral development The classic ABCDE model for floral organ identity show that ... -
Investigating Pattern Recognition And Bi-coordinate Sound Localization in the Tree Cricket Species Oecanthus Henryi
(2017-09-20)Acoustic communication, used by a wide variety of animals, consists of the signaler, the signal and the receiver. A change in the behaviour of the receiver after reception of the signal is a prerequisite for communication. ... -
Investigating spin transport across magnetic insulators and their interfaces
Spin transport across magnetic insulator/heavy metal (MI/HM) interfaces has been a topic of interest in spintronics. The spin Seebeck effect (SSE) and spin Hall magnetoresistance (SMR) are two phenomena that have ... -
Investigating Systematics In The Cosmological Data And Possible Departures From Cosmological Principle
(2013-06-11)This thesis contributes to the field of dark energy and observational cosmology. We have investigated possible direction dependent systematic signal and non-Gaussian features in the supernovae (SNe) Type Ia data. To detect ... -
Investigating the Impact of Habitat Disturbance and the Role of Functional Traits in a Tropical Butterfly Assemblage
(2018-07-09)Tropical habitats face a diverse range of anthropogenic threats. Two common and important threats to tropical biodiversity are invasive species and roads. Invasive plants are proposed to be a major threat to biodiversity ... -
Investigating the Intercarbonyl X...C' (X=O/S/N) Interactions in Short Peptides and Peptidomimetics. Evidence of charge->II* Interactions. Synthesis and Characterization of Thioimidate Isostere Containing Peptidomimetics
(2018-02-06)This thesis entitled “Investigating the Intercarbonyl X···C′ (X = O/S/N) Interactions in Short Peptides and Peptidomimetics. Evidence of Charge→π* Interactions. Synthesis and Characterization of Thioimidate Isostere ... -
Investigating the mechanisms of cancer drug resistance
Clinical chemo-resistance has posed a challenge to scientists and clinicians since the development of chemotherapeutics as anticancer strategy. Mechanisms of drug resistance continue to be a subject investigation amongst ... -
Investigating the Novel Roles of miR-9a and the Regulators of Mitochondrial Dynamics During the Development and Functioning of Indirect Flight Muscles in Drosophila melanogaster
The muscular system is a highly complex and important system in the body. Proper muscle physiology is critical for locomotion, digestion, circulation, reproduction as well as for metabolic and immune homeostasis. Defects ... -
Investigating the redox signaling mechanisms during HIV-TB co-infection
Oxidative stress has been at the forefront of HIV/AIDS-related pathophysiologies since the early days of its discovery. Overcoming HIV-1 latency, wherein, the virus remains integrated in the host chromatin, undetected and ... -
Investigating the role and regulation of Polypyrimidine tract binding protein (PTB) in isoform switching during muscle development in Drosophila melanogaster
Muscles are an excellent system to dissect the development, physiology and evolution of cell heterogeneity and isoform switching. The vertebrate skeletal muscles are composed of heterogeneous muscle fibres. These fibres ... -
Investigating the role of AMPK in mammary gland alveologenesis and lactation
AMP-activated kinase (AMPK) is an energy sensor that regulates cell growth and metabolism. Reports from our laboratory and others have shown the context-specific role of AMPK signaling in breast cancer. However, its role ... -
Investigating the role of an atypical dual-specificity phosphatase DUSP28 in mammalian cells
Dual-specificity phosphatases (DUSPs) belong to the protein tyrosine phosphatases (PTP) subfamily and dephosphorylate, both serine/threonine and tyrosine residues of proteins and non-protein substrates. A subgroup of ... -
Investigating the Role of Domain Swapping in Aggregation of Globular Proteins
The broad objective of this thesis involves computationally modeling protein aggregation with special emphasis on the role of cosolvents and misfolded states. Chapter 1 contrasts the effect of biologically relevant co-solvents ... -
Investigating the role of mantle convection in affecting surface deformation and topography in the Indian plate and the India-Eurasia collision zone
The India-Eurasia collision zone has been a subject of various studies that have tried to explain the forces behind the high elevation and large scale continental deformation in this region. However, the relative contribution ...