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Now showing items 2566-2585 of 8440
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Exploring The Role Of Purinergic Signaling In T Cell Activation
(2013-07-17)Adenosine 5’ triphosphate (ATP) is a molecule central to life for its role as the cellular energy currency, and a purine nucleotide which serves as a building block of RNA. Thus, on the backdrop of an indispensible ... -
Exploring The Role Of The Highly Conserved Residues In Triosephosphate Isomerase
(2014-08-11)This thesis discusses the structure-function studies on triosephosphate isomerase (TIM) from Plasmodium falciparum (Pf), directed towards understanding the roles of highly conserved residues by site derected mutagenesis. ... -
Exploring the roles of nucleoid-associated protein HU and two of its interacting proteins in Mycobacterium tuberculosis pathogenesis
The genome in prokaryotes is restricted to a membrane-less compartment termed nucleoid. The genome is maintained in the compacted state within the nucleoid with the help of three key cellular factors viz, macromolecular ... -
Exploring the Roles of Phase Variable HpyAII Restriction-modification System in the Human Pathogen Helicobacter pylori
Helicobacter pylori is a Gram-negative microaerophilic bacteria known to infect as much as 80% of some populations with an average morbidity range of around 50% of the world population. It has been recognized as a definitive ... -
Exploring the Semantics of Plan Diagrams
Database Management Systems (DBMS) are popular software packages for storing and managing enterprise data. Modern DBMS typically store data in the form of tables, called relations, and query the information using the ... -
Exploring the Unusual Properties and Non-canonical Roles of Promiscuous Restriction Endonuclease KpnI
Restriction modification (RM) systems are important components of bacterial immune system. Their primary function is to protect the bacteria from invading bacteriophages. Based on the subunit composition, enzyme properties ... -
Exploring Topological Phases of Matter using Density Functional Theory and Machine Learning Approaches
Topological phases of matter such as topological insulator (TI), quantum anomalous Hall insulator (QAHI), nodal line semimetal (NLSM), and triple point metal (TPM) can be realized by manipulating the spin-orbit coupling ... -
Exploring Topological Semimetallic Phases of Matter through First-Principles Calculations
In recent years, the study of topological phases of matter have received immense interest. Following the discovery of topological insulators, topological band theory has been extended to topological semimetals, characterized ... -
Exploring Transition Metal Oxides Towards Development of New Functional Materials : Lithium-ion Battery Cathodes, Inorganic Pigments And Frustrated Magnetic Perovskite Oxides
(2017-10-11)Transition metals (TMs) are ‘elements whose atoms have partially filled d-shell, or which can give rise to cations with an incomplete d-shell’. In TMs, the d-shell overlaps with next higher s-shell. Most of the TMs exhibit ... -
Exploring water dynamics and gas separations in graphene oxide surfaces and nanopores
Graphene oxide (GO) is a chemically functionalized graphene with various oxygen-containing functional groups, such as epoxy (-O-), hydroxyl (-OH), and carboxyl (-COOH) on the basal plane. As a consequence, GOs have hydrophilic ... -
Exploring Welfare Maximization and Fairness in Participatory Budgeting
Participatory budgeting (PB) is a voting paradigm for distributing a divisible resource, usually called a budget, among a set of projects by aggregating the preferences of individuals over these projects. It is implemented ... -
Exponential Resummation of QCD at Finite Chemical Potential
A comprehensive study of the QCD phase diagram is one of the challenging and open problems in high energy physics. Having significant astrophysical implications, this is also important in constructing the chronological ... -
Expression Profiling Of Genes Regulated By TGF-β : Role Of Multiple Signaling Pathways
(2009-05-12)Transforming growth factor-β (TGF-β) is the proto-type member of a super family of secreted proteins comprised of several structurally related, but functionally divergent proteins like the BMP, activin, inhibin, mullerian ... -
Extended finite simulations of cohensive crack propagation under mode-3 loading
Modeling of propagating discontinuities (cracks) is a challenging problem in the field of computational mechanics. Numerical techniques such as Finite Difference Method (FDM), Boundary Element Method (BEM), and Finite ... -
An Extended Integrated Model Of Designing
(2014-06-20)Product success is a major goal of designing and design research. Designing involves developing systems. A system interacts with its environment to satisfy its requirements. Therefore, designing should involve developing ... -
Extended Range Predictability And Prediction Of Indian Summer Monsoon
(2009-03-17)Indian summer monsoon (ISM) is an important component of the tropical climate system, known for its regular seasonality and abundance of rainfall over the country. The droughts and floods associated with the year-to-year ... -
Extended Reality based Digital Twin of Arc Welding
Arc welding is an important permanent joining process widely used across multiple industries such as transportation, infrastructure construction and equipment manufacturing. However, the inherent high-energy physics and ...