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Now showing items 1985-2004 of 6421
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Exploring Protein-Nucleic Acid Interactions Using Graph And Network Approaches
(2009-09-22)The flow of genetic information from genes to proteins is mediated through proteins which interact with the nucleic acids at several stages to successfully transmit the information from the nucleus to the cell cytoplasm. ... -
Exploring Soft Matter and Modified-Liquid Electrolytes for Alkali metal (Li, Na) Based Rechargeable Batteries
The current upsurge in demand for high energy density batteries for applications across industries ranging from small scale portable electronics, electric automobiles to storage grids, has led to research in next generation, ... -
Exploring Structure and Reactions : Computational Studies on Three-Membered Rings, Metal-Boron Multiple Bonds and Biradical Reactions
(2018-04-06)The utility of computational study lies not only in rationalizing a chemical phenomenon but also in its predictive value. Broadly, the scope of my research work includes understanding of the structure and bonding of molecules ... -
Exploring the Evolution of Cellobiose Utilization in Shigella Sonnei And the Conservation of ChbG Orthologs in Eukaryotes
(2017-10-11)The chb operon constitutes the genes essential for utilization of chitooligosaccharides in Escherichia coli and related species. The six genes of the operon code for a transcriptional regulator (ChbR) of the operon, a ... -
Exploring the Fundamental Limits of Information-Theoretically Secure Key Generation and DNA-Based Data Storage
In this dissertation, we carry out an exploration of the fundamental limits of information-theoretic security in two different settings: multiterminal key agreement and DNA-based data storage. Most of the dissertation ... -
Exploring the Inherent Saliency in Visual Data through Convolutional Neural Networks
Saliency plays a key role in various computer vision tasks. Extracting salient regions from images and videos has been a well-established problem in computer vision. Determining salient regions in an image or video has ... -
Exploring the Marine Algicolous Endophytic Fungi: A Promising Source of Novel Cancer Therapeutics
Cancer is the second leading cause of mortality globally, with over 6 million new cases diagnosed annually. Research on effective therapies is crucial due to the disease's complexity. Natural materials in chemotherapy have ... -
Exploring the role of low complexity protein sequence in regulating RNA granule dynamics and translation control
RNA granules are conserved membraneless mRNP complexes that play an important role in determining mRNA fate by affecting translation repression and mRNA decay. Processing bodies (P-bodies) harbor enzymes responsible for ... -
Exploring The Role Of Purinergic Signaling In T Cell Activation
(2013-07-17)Adenosine 5’ triphosphate (ATP) is a molecule central to life for its role as the cellular energy currency, and a purine nucleotide which serves as a building block of RNA. Thus, on the backdrop of an indispensible ... -
Exploring The Role Of The Highly Conserved Residues In Triosephosphate Isomerase
(2014-08-11)This thesis discusses the structure-function studies on triosephosphate isomerase (TIM) from Plasmodium falciparum (Pf), directed towards understanding the roles of highly conserved residues by site derected mutagenesis. ... -
Exploring the Roles of Phase Variable HpyAII Restriction-modification System in the Human Pathogen Helicobacter pylori
Helicobacter pylori is a Gram-negative microaerophilic bacteria known to infect as much as 80% of some populations with an average morbidity range of around 50% of the world population. It has been recognized as a definitive ... -
Exploring the Unusual Properties and Non-canonical Roles of Promiscuous Restriction Endonuclease KpnI
Restriction modification (RM) systems are important components of bacterial immune system. Their primary function is to protect the bacteria from invading bacteriophages. Based on the subunit composition, enzyme properties ... -
Exploring Topological Phases of Matter using Density Functional Theory and Machine Learning Approaches
Topological phases of matter such as topological insulator (TI), quantum anomalous Hall insulator (QAHI), nodal line semimetal (NLSM), and triple point metal (TPM) can be realized by manipulating the spin-orbit coupling ... -
Exploring Transition Metal Oxides Towards Development of New Functional Materials : Lithium-ion Battery Cathodes, Inorganic Pigments And Frustrated Magnetic Perovskite Oxides
(2017-10-11)Transition metals (TMs) are ‘elements whose atoms have partially filled d-shell, or which can give rise to cations with an incomplete d-shell’. In TMs, the d-shell overlaps with next higher s-shell. Most of the TMs exhibit ... -
Exploring water dynamics and gas separations in graphene oxide surfaces and nanopores
Graphene oxide (GO) is a chemically functionalized graphene with various oxygen-containing functional groups, such as epoxy (-O-), hydroxyl (-OH), and carboxyl (-COOH) on the basal plane. As a consequence, GOs have hydrophilic ... -
Exploring Welfare Maximization and Fairness in Participatory Budgeting
Participatory budgeting (PB) is a voting paradigm for distributing a divisible resource, usually called a budget, among a set of projects by aggregating the preferences of individuals over these projects. It is implemented ... -
Exponential Resummation of QCD at Finite Chemical Potential
A comprehensive study of the QCD phase diagram is one of the challenging and open problems in high energy physics. Having significant astrophysical implications, this is also important in constructing the chronological ... -
Expression Profiling Of Genes Regulated By TGF-β : Role Of Multiple Signaling Pathways
(2009-05-12)Transforming growth factor-β (TGF-β) is the proto-type member of a super family of secreted proteins comprised of several structurally related, but functionally divergent proteins like the BMP, activin, inhibin, mullerian ...