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Biochemical Characterization Of Heat Shock Protein 90 From Plasmodium Falciparum
(2013-06-07)
Molecular chaperones are a group of proteins which maintain cellular homeostasis by assisting de novo protein folding and their refolding to native state after destabilization due to external stress. They are also known ...
Functional Characterization And Regulation Of UvrD Helicases From Haemophilus Influenzae And Helicobacter Pylori, And Recj Exonuclease Fron Haemophilus Influenzae
(2013-04-01)
DNA repair processes are crucial for mutation avoidance and the maintenance of genetic integrity in all organisms. Organisms rely on repair processes to combat genotoxic stress imposed by hostile host environment, and ...
Insights Into The Mechanism Of Polyprotein Processing Of Sesbania Mosaic Virus And Characterization Of The Polyprotein Domains
(2013-06-10)
1. Viruses are obligate parasites that hijack the host cell machinery to synthesize
their own gene products and for their propagation. In order to establish a
successful viral infection, viruses have evolved different ...
Exploring The Role Of Purinergic Signaling In T Cell Activation
(2013-07-17)
Adenosine 5’ triphosphate (ATP) is a molecule central to life for its role as the
cellular energy currency, and a purine nucleotide which serves as a building block of RNA. Thus, on the backdrop of an indispensible ...
Mechanism Of RAG Action As A Structure-Specific Nuclease : Implications In Genomic Instability In Lymphoid Cells
(2013-07-18)
Recombination Activating Genes (RAGs) orchestrate the process called V (D) J recombination, which enables the vertebrate adaptive immune system to specifically recognize millions of antigens. During this recombination ...
Characterization Of HP1369-HP1370 From Helicobacter Pylori : A Novel ε Type N6 –Adenine Methyltransferase
(2013-07-18)
Helicobacter pylori is one of the most genetically diverse bacterial species that successfully colonizes at least 50% of the world population. It has been associated with humans for thousands of years and most probably ...
Processing Of DNA Recombination And Replication Intermediates By Mycobacterium Tuberculosis RuvA And RuvB Proteins
(2013-06-14)
Homologous recombination (HR) is a highly conserved cellular process involved in the
maintenance of chromosomal integrity and generation of genetic diversity. Biochemical and genetic studies have suggested that HR is ...
Production Of Anticancer Drug Taxol And Its Precursor Baccatin III By Fusarium Solani And Their Apoptotic Activity On Human Cancer Cell Lines
(2013-06-24)
Taxol (generic name paclitaxel), a plant‐derived antineoplastic agent, was
originally isolated from the bark of the Pacific yew, Taxus brevifolia. Obtaining
taxol from this source requires destruction of trees. It has ...