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Mxr1p is a Global Regulator of Multiple Metabolic Pathways in the Methylotrophic Yeast Pichia Pastoris
(2018-03-01)
The present study is aimed at examining the ability of Pichia pastoris to utilize acetate and amino acids as the sole sources of carbon. We demonstrate that the zinc finger transcription factor Mxr1p, which is a positive ...
Uncovering the Role of Mitochondrial Co-chaperones and Artificial Antioxidants in Cellular Redox Homeostasis
(2018-02-14)
The role of mitochondria is multidimensional and ranges in vast areas, including apoptosis, cellular response towards stress, metabolism, which is regulated by a plethora of proteins, acting together to maintain cellular ...
Isolation And Identification of Tropane Alkaloid Producing Endophytic Fungi from Datura Metel L., And Studies on Colletotrichum Boninense Recombinant Putrescine N-mehtyltransferase
(2017-10-11)
Datura metel is a herbaceous plant found in almost all tropical parts of the world. It belongs to the family Solanaceae whose members, viz. Duboisia, Atropa, Hyoscyamus and Datura plants are known to produce tropane ...
Host Gene Expression Profiling of Japanese Encephalitis Virus Infected cells : Identification of Novel Pro- and Anti-viral Genes
(2017-11-27)
Japanese encephalitis virus (JEV), a mosquito-borne flavivirus is the causative agent of Japanese encephalitis (JE). The disease affects mostly children and around 30000– 50000 cases of JE and up to 15000 deaths are reported ...
Physiological And Exogenous Means of Regulating DNA Damage Response : Insights into Mechanisms of DNA Repair And Genomic Instability
(2017-09-23)
Maintenance of genomic integrity with high fidelity is of prime importance to any organism. An insult which may result in compromised genome integrity is prevented or its consequences are monitored by advanced cellular ...
Evaluation of Alternate DNA Structures at c-MYC Fragile Region Associated with t(8;14) Translocation And Role of GNG Motifs During G-quadruplex Formation
(2017-10-11)
Watson-Crick paired B-form DNA is the genetic material in most of the biological systems. Integrity of DNA is of utmost importance for the normal functioning of any organism. Various environmental factors, chemicals and ...