etd AT Indian Institute of Science: Recent submissions
Now showing items 901-920 of 6756
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Investigations on Generation of Multilevel 24-Sided Polygonal Voltage Space Vector Structures Without Vector Averaging for Variable Speed Drives
Induction motors are mainly powered by two-level inverters in low-voltage, low-power drive applications. For medium and high voltage applications, a conventional two-level inverter needs high voltage rated switches, ... -
Exploring the role of low complexity protein sequence in regulating RNA granule dynamics and translation control
RNA granules are conserved membraneless mRNP complexes that play an important role in determining mRNA fate by affecting translation repression and mRNA decay. Processing bodies (P-bodies) harbor enzymes responsible for ... -
Optimal Placement and Traffic Steering of VNFs and Edge Servers using Column Generation in Data Center Networks
Telecom Service Providers (TSPs) were traditionally dependent on physical devices to provide end-to-end communication. The services provided were high quality and stable but low in agility and hardware-dependent. As the ... -
On Plug-and-Play Regularization using Linear Denoisers
The problem of inverting a given measurement model comes up in several computational imaging applications. For example, in CT and MRI, we are required to reconstruct a high-resolution image from incomplete noisy measurements, ... -
INTERPIN: identifying INtrinsic transcription TERminators, hairPINs in bacteria
The conversion of DNA to RNA through transcription is an important step in the life cycle of every organism. It ensures that the genetic information in DNA is converted through RNA into instructions/blueprints for the ... -
Understanding the role of mtHsp70 in regulating mitochondrial homeostasis: revealing its significance in Congenital Sideroblastic Anemia progression
Mitochondria are ubiquitous organelles placed at the nexus of several metabolic and signaling pathways essential for cell survival. Therefore, maintaining a healthy and functional organelle becomes paramount for the cell. ... -
Multi-vehicle anticipation-based models for describing driver behaviour in heterogeneous and disorderly traffic conditions
Driver behaviour models are widely used in the traffic engineering literature and practice. They are used for understanding drivers’ manoeuvring decisions in traffic streams. They also form the building blocks of microscopic ... -
Edible Battery Design for Bio-Medical applications
This thesis is focused on the development of digestible electronics for healthcare. The vision is the development of an edible pill that performs diagnosis inside the body. Any such edible device needs an energy source ... -
Design and development of lateral force-controlled tribosystems
In a tribo-system, the frictional resistance during a sliding process depends on several parameters. These parameters include the interacting materials, their surface topography, contact conditions such as normal load, ... -
Unraveling the multifaceted interactions between the tumor cell hierarchy and the stroma: Implications on tumor growth
In this study, we have functionally characterized the roles of SEZ6, a GSC-specific protein, and FMOD, a DGC-specific protein, in inducing tumor angiogenesis. Angiogenesis being a crucial requirement for both tumor initiation ... -
Cerium Oxide-based Degradable Polymer Nanocomposites for Bone Tissue Engineering
The incidences of bone-related disorders is growing steeply worldwide because of acute trauma, diseases related to aging, and obesity. Bone has a natural regenerative capacity to repair and regenerate fractures and small ... -
An Investigation of the Characteristics of Monsoon Low Pressure Systems in the Present Climate and their Sensitivity to Topography and Climate Change
Monsoon Low-Pressure Systems (LPS) are synoptic-scale tropical disturbances that periodically form over the Indian subcontinent during the summer monsoon season (June-September). Apart from being a lifeline to agriculture, ... -
Insights into mRNA recruitment by eukaryotic initiation factor 4 during translation in Saccharomyces cerevisiae
Ribosomes are responsible for synthesizing proteins in the cells by using mRNA as the template. However, the ribosomes cannot perform this function without the help of other protein factors. Different factors are required ... -
Structural and biochemical studies on mycobacterial Uracil-DNA glycosylase (Ung) and MutT1, key proteins involved in maintaining the genomic integrity in Mycobacteria
Maintaining genomic integrity is indispensable for the survival and propagation of an organism. Failure to do so can cause mutations involving structural and functional aberrations, leading to severe diseases. The causative ... -
Learning Invariants for Verification of Programs and Control Systems
Deductive verification techniques in the style of Floyd and Hoare have the potential to give us concise, compositional, and scalable proofs of the correctness of various kinds of software systems like programs and control ... -
Stop codon readthrough of NNAT mRNA and its role in neuronal differentiation
Protein synthesis terminates at the first stop codon encountered by the ribosome. In stop codon readthrough, translation termination is suppressed, enabling the ribosomes to continue translation beyond the canonical stop ... -
HYDRA: A Dynamic Approach to Database Regeneration
Database software vendors often need to generate synthetic databases for a variety of applications, including (a) Testing database engines and applications, (b) Data masking, (c) Benchmarking, (d) Creating what-if scenarios, ... -
Understanding the role of paraspeckle components NEAT1 and PSPC1 in HCV life cycle and pathogenesis
Hepatitis C virus (HCV) is an enveloped, small, icosahedral, positive-sense single-stranded RNA virus that belongs to the Hepacivirus genus and the Flaviviridae family. HCV causes acute and chronic hepatitis which can range ... -
Transcriptional regulation of a microRNA encoding gene MIR319C during leaf development in Arabidopsis thaliana
The evolutionarily conserved microRNA miR319 and its target transcription factors encoded by five CIN-TCPs (TCP2, 3, 4, 10 & 24) regulate leaf morphogenesis in Arabidopsis by triggering the division to differentiation ... -
2,3-Dideoxy Sugars in Glycoconjugations and Cyclic Oligosaccharide Synthesis
2,3- Dideoxy sugars are versatile synthons for organic synthesis. The applications are diverse in biological systems and organic synthesis. In the first part of the thesis, 2,3-unsaturated sugars are used for the ...