etd AT Indian Institute of Science: Recent submissions
Now showing items 681-700 of 6861
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Establishment of a knock-in mouse model expressing a hypomorphic variant of receptor guanylyl cyclase C
Receptor guanylyl cyclase C (GC-C, gene GUCY2C) is expressed on the apical surface of the intestinal epithelial cells and gets activated by the endogenous ligands guanylin and uroguanylin. Heat-stable enterotoxin (ST) ... -
Effect of Processing Mg-6zn-0.2ce Through High-pressure Torsion on Its Use as a Biomaterial
Here, we investigate the effect of high-pressure torsion (HPT), a severe plastic deformation process, on the mechanical properties, corrosion, and cytotoxicity of Mg-6Zn-0.2Ce alloy, a candidate material for bioresorbable ... -
Synthesis and X-ray Crystallographic Studies of Salts, Co-crystals, Solvates of some Amine containing Active Pharmaceutical Ingredients and In-situ Cryo Crystallographic Studies on some Organic Liquids
Chapter I describes the general introductory note to describe the common terms like crystalline solids, properties, and their uses pharmaceutical industry. The definition of common terms like Salts, Co-crystal, solvates ... -
Deciphering the biochemical and biophysical properties of the Holliday junction resolvases RuvC and RuvX from Mycobacterium smegmatis
Homologous recombination (HR) is a ubiquitous cellular process that occurs in all three domains of life as well as in DNA and RNA viruses. In eukaryotes, HR is critically important for homology-directed DNA repair (HDDR) ... -
Astrocytes regulate oligodendrocyte development and myelination in the mammalian brain
Oligodendrocytes (OLs), a type of glial cell, are the main myelinating cells of the mammalian central nervous system (CNS), enabling efficient saltatory mode of nerve conduction. On the other hand, astrocytes, another glial ... -
Unravelling the kinematics, dynamics and structure of galaxies using H I - 21cm observation
The advent of the multi-wavelength observations of galaxies in this recent era gives us the opportunity to study the details of the different pivotal facets of galactic astrophysics. Among the observations in different ... -
Advances in Architecturing of Large-Scale Photovoltaics: Packaging and Incidence Angle Agnostic Hierarchical Nanostructures
Encapsulant of Graphene embedded polymer that exhibits low permeability to moisture and oxygen were used as a packaging material for OPVDs. Graphene-Surlyn encapsulated and unencapsulated devices were stored both in ambient ... -
Structure and dynamics of quantum supercooled liquids:Insights from molecular dynamics simulations
Supercooled liquids are formed when a liquid is cooled below the melting temperature, avoiding crystallization. The system gets trapped in one of the many metastable states in the free energy surface. In supercooled state, ... -
Secure Computation Protocol Suite for Privacy-Conscious Applications
As an alternative to performing analytics in the clear, there is an increasing demand for developing privacy-preserving solutions that aim to protect sensitive data while still allowing for its efficient analysis. Among ... -
Insights into life-cycle stage transition of Trichomonas vaginalis and advancement in its diagnosis
Trichomonas vaginalis is a protozoan parasite and the causative agent of the most common non-viral, sexually transmitted disease (STD) in humans known as trichomoniasis. WHO estimates more than 270 million cases of ... -
Capacity Computation and Coding for Input-Constrained Channels
The setting of the transmission of information over noisy, binary-input, memoryless channels is today well-understood, owing to the work of several information theorists, beginning with Claude Shannon. It is known that it ... -
Optical and Electrical Studies of Hybrid Nanomaterial Composites Based on Noble Metal Nanostructures
Localized surface plasmon resonance (LSPR) in noble metal nanoparticles like gold (Au) and silver (Ag) results in enhancements in optical absorption and scattering by the nanoparticles, accompanied by a dramatic ... -
Experimental and numerical study of mechanics and mechanisms of mode I fracture of a textured magnesium alloy
In recent years, magnesium alloys have gained increasing application in the automotive industry to achieve weight reduction in vehicle components which is crucial for enhancing fuel efficiency and meeting stringent emission ... -
Collective Phototaxis of Chlamydomonas reinhardtii Cells
Microorganisms are omnipresent in our life and the environment, such as microbes in the gut, spermatozoa in reproductive organs, algae and protozoa in the aquatic ecosystem, and bacterial colonization and infection. ... -
Understanding the interplay between immune response and virus evolution
RNA viruses are the underlying cause of many human diseases, including the common cold, influenza, dengue fever, and COVID-19. Their ability to evolve rapidly makes them challenging to tackle, resulting in public health ... -
Molecular Approaches and Structural Insights into Correlated Triplet Pair Dynamics in Intramolecular Singlet Fission
Singlet Fission (SF) is a bichromophoric process whereby a singlet exciton is converted to two triplet excitons through an overall spin-conserved process. The last decade has seen an upsurge in SF research driven by its ... -
Studies on Metal Hydride Based Multifunctional Coupled Thermal Battery Systems
Thermal energy storage systems (TESS) based on chemisorption/thermochemical reactions have several advantages over conventional thermal storage systems based on sensible and latent heat. The advantages include high energy ... -
Atto-second Dynamics in Molecular Systems
The thesis describes the attosecond dynamics of small molecular systems, focusing on ionization delay times and hole migration delay times. These time delays are some of the fastest events in electronic dynamics. When an ... -
Machine learning and density functional theory assisted insights into the mechanical and oxidation properties of nickel-based superalloys
Due to global warming and increasing fuel costs, there is a constant thrust toward increasing fuel efficiency and reducing the emissions of gas-turbine engines, which are made out of superalloys. New superalloy materials, ... -
Nanomaterials for Magnetism and Catalysis
Nanomaterials possess unique physical and chemical properties allowing for advancement and innovation in diverse scientific and technological fields. The remarkable magnetic and catalytic properties of these nanomaterials ...