etd AT Indian Institute of Science: Recent submissions
Now showing items 681-700 of 6711
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Elucidating the role of SNARE Syntaxin 1A in regulating lysosome and melanosome function
SNAREs are transmembrane proteins that localize to specific membranes and facilitate the process of membrane/vesicle fusion. SNAREs mediate the fusion by binding with their respective cognate SNAREs. SNAREs mediate the ... -
On some canonical metrics on holomorphic vector bundles over Kahler manifolds
This thesis consists of two parts. In the first part, we introduce coupled Kähler- Einstein and Hermitian-Yang-Mills equations. It is shown that these equations have an interpretation in terms of a moment map. We identify ... -
Exponential Resummation of QCD at Finite Chemical Potential
A comprehensive study of the QCD phase diagram is one of the challenging and open problems in high energy physics. Having significant astrophysical implications, this is also important in constructing the chronological ... -
Characterization of Neuroprotective Reactive Astrocytes in the Aging Mammalian Brain
The brain manifests cognitive deficits in aging and becomes more vulnerable to neurodegeneration. Astrocytes play several critical roles in the brain, including synapse formation, maturation, elimination, and synaptic ... -
Improved Methods for Filtration, Drainage and Structural Evaluations With and Without Geocomposites for Subsurface Drainage of Pavements
Pavements are continuously exposed to the environment leading to ingress of water from multiple sources that structurally weakens the pavement materials. The conventional solution for drainage requires granular material ... -
Isolation, structure elucidation and increasing anticancer efficacy of an anti-cancer secondary metabolite from a marine-derived endophytic fungus, Aspergillus species
Cancer is the leading cause of mortality globally, contributing to ~10 million fatalities in 2020, or roughly one in every six deaths, according to global cancer statistics 2020. Around 50% of all small molecules approved ... -
Interaction of distinguished varieties and the Nevanlinna-Pick interpolation problem in some domains
This thesis explores the interplay between complex geometry and operator theory, focusing on characterizing certain objects from algebraic geometry. Two concepts that have been of prime importance in recent times in the ... -
Investigating the role of an atypical dual-specificity phosphatase DUSP28 in mammalian cells
Dual-specificity phosphatases (DUSPs) belong to the protein tyrosine phosphatases (PTP) subfamily and dephosphorylate, both serine/threonine and tyrosine residues of proteins and non-protein substrates. A subgroup of ... -
Towards Robustness of Neural Legal Judgement System
Legal Judgment Prediction (LJP) implements Natural Language Processing (NLP) techniques to predict judgment results based on fact description. It can play a vital role as a legal assistant and benefit legal practitioners ... -
First principles-based study of monolayer WSSe and metal interface.
The semiconductor-metal interface is universal for any electron device. Two-dimensional semiconductors have the advantages of free dangling bonds and atomically flat surfaces, making them promising materials to substitute ... -
Vision-driven Tele-Operation for Robot Manipulation
It’s worth the time to acknowledge just how amazingly well we humans can perform tasks with our hands. Starting from picking up a coin to buttoning up our shirts. All these tasks for robots are still at the very forefront ... -
Delineating the dynamics of neutrophil response in multiple inflammatory stimuli and its consequences
In this thesis, we investigate the regulation of neutrophils, an important component of the immune system, and its implications on inflammation and pathological conditions. We use biomaterial implants to induce chronic ... -
A stable Strontium isotopic (δ88/86Sr) study of seawater from the Bay of Bengal, coastal groundwater from the Bengal Basin, and the Ganges, Brahmaputra, Mahanadi, and Godavari rivers in India
Strontium (Sr) is an alkaline earth element that has four naturally occurring stable isotopes, 84Sr, 86Sr, 87Sr and 88Sr. During measurements of the radiogenic Sr isotope ratio (87Sr/86Sr), which is a widely used tracer ... -
Algorithms for Achieving Fairness and Efficiency in Matching Problems
Matching problems arise in numerous practical settings. Fairness and efficiency are two desirable properties in most such real world scenarios. This dissertation work presents new approaches and models for capturing and ... -
Search for dark matter produced in association with a Higgs boson decaying to a pair of bottom quarks in proton-proton collisions at √s= 13 TeV using CMS 2017 and 2018 data
The discovery of the Higgs boson has opened a new portal to search for Dark Matter(DM). Since DM does not interact in the CMS detector, searches rely on the missing transverse energy in association with a visible SM ... -
Privadome: A System for Citizen Privacy in the Delivery Drone Era
E-commerce companies are actively considering the use of delivery drones for customer fulfillment, leading to growing concerns around citizen privacy. Drones are equipped with cameras, and the video feed from these cameras ... -
Experimental Investigations on Ramp-induced Large Separation Bubble in a Hypersonic Flow
Shockwave Boundary Layer Interactions (SBLIs) are ubiquitous in supersonic/ hypersonic flows and often lead to the separation of the boundary layer. These separations can be broadly classified into small and large ... -
Correlations in multispecies asymmetric exclusion processes
The main aim of this thesis is to study the correlations in multispecies exclusion processes inspired by the research of Ayyer and Linusson (Trans. AMS., 2017) where they studied correlations in the multispecies TASEP on ... -
CodeQueries: Benchmarking Query Answering over Source Code
Software developers often make queries about the security, performance effectiveness, and maintainability of their code. Through an iterative debugging process, developers analyze the code to find answers to these ... -
Investigation of Au-free AlGaN/GaN HEMT on Silicon with substrate transfer process: From Ohmic contacts to RF performance
The technological importance of III-nitride based high electron mobility transistors (HEMTs) for power switching and RF applications is growing rapidly, owing to two advantageous electrical properties. While high sheet ...