etd AT Indian Institute of Science: Recent submissions
Now showing items 401-420 of 6746
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Understanding the interaction mechanism of bacterial virulence factors and effector proteins with host lipid membrane using single particle cryo-electron microscopy
Pathogenic bacteria employ an array of biological macromolecules and cellular structures that help in the initiation and progression of disease in host organism. These ‘virulence factors’ can either be secreted by the ... -
Role of Sirtuin 2 in the development of tissue fibrosis
Wound healing is a crucial physiological process required for the healthy lifespan of an organism. Dysregulation in the process of wound healing leads to the production of excess extracellular matrix leading to fibrosis. ... -
An Explainable Hierarchical Class Attention Model for Legal Appeal Automation
Judicial systems worldwide are overburdened due to the limited number of legal professionals. The digitization of legal processes has resulted in abundant legal data, paving the way for the development of legal automation ... -
Flux Rate Controlled Harmonic Filtering of Integrated Magnetic-Based Isolated-Inverter Topologies and Dynamically Variable Inductors
An intermediate filtering stage is mandatory to deliver smooth sinusoidal output voltage across the load. Several multilevel and modular multilevel-based inverter topologies are reported in the literature to reduce the ... -
Some Aspects of Weighted Kernel Functions on Planar Domains
The broad aim of this thesis is to study some aspects of weighted kernel functions. In particular, this thesis has been driven by three principal goals: First, to study the boundary behaviour of weighted Bergman kernels. ... -
Frequency Domain Photoacoustic Signal Analysis for Temperature Sensing
Monitoring temperature in biological tissue is vital for different therapy applications like photo-thermal therapy, high-intensity focused ultrasound therapy, etc. Photoacoustic imaging has been used for volumetric temperature ... -
Performance Analysis of Orthogonal Time Frequency Space Modulation in High-Doppler Channels
Next generation wireless systems are envisioned to offer dependable and consistent user experience across a wide range of environments, including high-mobility scenarios involving high-speed trains, aircrafts, and ... -
A co-kurtosis tensor based featurization of chemistry for scalable combustion simulations
For turbulent reacting flow systems, identification of low-dimensional representations of the thermo-chemical state space is vitally important, primarily to significantly reduce the computational cost of device-scale ... -
Interfacial oscillations and atomization of liquid jets from non-circular orifices
Understanding the flow behaviour of liquid jets discharging from orifices is essential for several applications such as fuel spraying, ink-jet printing, aerosol devices in pharmaceutical industries, micro-machined fuel ... -
Paper-Based Point-of-Care Diagnostic Tools: Electrokinetic Nucleic Acid Extraction and Saliva-Based Glucose Detection for Diabetes Monitoring
Currently, we face a global challenge posed by the dual burden of chronic diseases such as diabetes and infectious diseases such as tuberculosis (TB). Low-and middle-income countries are disproportionately overburdened by ... -
Low–Speed Impact Mechanics and Fragmentation of Wooden Panels: Characterization of Indian Woods
Low–speed impact (LSI) of brittle structural panels by rigid bodies causes significant damage, evident in familiar scenarios like the breaking of monolithic and laminated glass panes due to stone pelting, punching a hole ... -
Advanced Light Sheet Volume Flow Cytometry (VFC/iLIFE) and Spectroscopy System for Cell Biophysics and Clinical Biology
Optical imaging is paramount for disease diagnosis and to access its progression over time. The developed light sheet-based optical flow imaging techniques, known as Volume Flow Cytometry(VFC/iLIFE), and related techniques ... -
Quantitative Nonlinear Optical Microscopy with Applications in Nanostructure Imaging and Cancer Biology
Quantitative Nonlinear Optical Microscopy with Applications in Nanostructure Imaging and Cancer Biology Abstract: Nonlinear optical microscopy is a powerful imaging technique that has been used for imaging for diverse ... -
Bacterial cellular heterogeneity in inducible gene expression and drug susceptibility
Biological processes are inherently noisy, and such stochasticity can result in significant cell to cell variability in isogenic bacterial populations. Functionally, cellular heterogeneity can have significant impact on ... -
Role of Oxygen Vacancies in Modification of Electronic Structure of Bulk Oxides
Emergent phenomena in oxides have been receiving a lot of experimental and theoretical interest in the recent decade. In general, oxides host a rich diversity of defects and several new emergent phenomena such as 2-DEG ... -
A geochemical and Ca, Sr, Nd isotopic study of the mantle: case studies of Kimberlites, Ophiolites, Abyssal Peridotites, and Layered Igneous Complexes
The Earth’s mantle constitutes 67% of its mass and despite mantle convection, it is geochemically and isotopically heterogeneous as evident from the compositions of mantle derived basaltic melts. It is a dynamic system ... -
Investigation of inter-layer charge transfer process in optically excited graphene and transition metal dichalcogenide-based heterostructures
Light-matter interaction of two-dimensional (2D) materials and their van der Waals hybrids have gained significant interest in the past few years as they offer an intriguing platform for studying fundamental physical ... -
Advancements in Nucleic Acid Lateral Flow Assay
In recent decades, the demand for rapid and precise nucleic acid amplification tests (NAATs) has grown significantly, driven by the need to address pandemics like COVID-19 and diagnose infectious diseases such as ... -
An Exploration of Molecular Recognition Mechanisms and Ligand Induced Transitions in Biomolecules
Molecular recognition refers to processes through which biological macromolecules interact with each other or other small molecules through noncovalent interactions to form specific complexes. Applying molecular recognition ...