etd AT Indian Institute of Science: Recent submissions
Now showing items 3001-3020 of 6965
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Plasticity of Intrinsic Excitability in Fast Spiking Interneurons of the Dentate Gyrus & Its Implications for Neuronal Network Dynamics
Inhibitory GABAergic neurons, although forming a minor proportion of the neuronal population in the central nervous system, have been reported to be crucial for different physiological states of the brain. Among the vast ... -
Cost Effective Multi-role Active EMI Filters for Switched Mode Converters
Switched mode power converters are a major source of conducted electromagnetic interference (EMI). The popular technique for mitigation of conducted EMI uses EMI filters. EMI filters may be classified in two types based ... -
Neural Mechanisms underlying the planning of sequential saccades
Saccades are rapid eye movements that we continually make (about 2-3 times per second) to look around and scan our visual environment. Though we effortlessly execute saccadic eye movements all the time, they are not just ... -
Discharge Plasma based NOx Abatement in Engine Exhaust Assisted by Industry Wastes : A Parametric Evaluation with Diesel Fuels and Corona Electrodes
Diesel engines contribute to a large percentage of oxides of nitrogen (NOx) emission in the atmosphere. The NOx primarily consists of nitric oxide (NO) and nitrogen dioxide (NO2). With depleting fossil fuel supplies ... -
Studies on Oxovanadium(IV) Complexes for Photocytotoxicity and Cellular Imaging
The thesis work deals with different aspects of the chemistry of oxovanadium(IV) complexes, their interaction with DNA, photo-induced cleavage of double-stranded DNA, photocytotoxic effect on cancer and normal cells in ... -
Accelerated and Accurate Alignment of Short Reads in High Throughput Next Generation Sequencing [NGS] Platforms
The genome of an organism encompasses the unique set of genetic instructions for every individual in a species. The genome, in totality, guides the course of evolution, development, genetic and epigenetic growth factors ... -
Theoretical and Experimental Study of Three-Dimensional Chiro-Optical Materials
Light-matter interactions at the nanoscale have been widely studied over the past few decades. In particular, the interaction of light with asymmetric nanostructures has harbored the interests of chemists, biologists and ... -
Enantioselective Carbon-Carbon and Carbon-Heteroatom Bond Formation : From Bifunctional to Anion-Binding Catalysis
The thesis entitled “Enantioselective Carbon-Carbon and Carbon-Heteroatom Bond Formation: from Bifunctional to Anion-Binding Catalysis” is divided into four chapters. Chapter 1: Organocatalytic Asymmetric Direct Vinylogous ... -
Algiculture - A Novel Algae Cultivation Technique for Sustinable Algal Biofuel Production and Capture of Green House Gases
Algal biofuel has been shown to have great potential to solve the World’s sustainable energy crisis but technologies for large-scale cultivation are still elusive. While photobioreactors meet very high value algal products ... -
Exploring the Roles of Phase Variable HpyAII Restriction-modification System in the Human Pathogen Helicobacter pylori
Helicobacter pylori is a Gram-negative microaerophilic bacteria known to infect as much as 80% of some populations with an average morbidity range of around 50% of the world population. It has been recognized as a definitive ... -
Functional Insights into the Canonical and Non-canonical Roles of the Fission Yeast Splicing Factor SpPrp16
The spliceosome is a large multi-megadalton RNA-protein machine which facilitates the removal of introns from eukaryotic nascent pre-mRNAs by two concerted transesterification reactions. The spliceosome is comprised of ... -
Delineating the Roles for WNT Signaling During PRRs Driven Inflammatory Responses : Implications for Host-Pathogen Interaction
The mammalian immune system consists of the innate and adaptive arm/s that protect the host against pathogenic infections in a highly coordinated process involving multiple steps. Innate immune cells such as macrophages ... -
Structure- Function Studies on Triosephosphate Isomerase : Some Old Questions, Some New Insights
This thesis describes biophysical, kinetic, structural, and sequence conservation analysis of the glycolytic enzyme triosephosphate isomerase (TIM). TIM catalyses the diffusion limited isomerization of D-glyceraldehyde-3-phospahte ... -
Study of Dynamics, Thermal and Rheological Properties of Polymer Grafted Nanoparticle-polymer Blend
We studied dispersion state and dynamics of polymer grafted nanoparticle in photopolymer matrix nanoparticle-polymer blend- and their thermal and rheological properties. While thinking about a nanoparticle-polymer blend, ... -
Pore Forming Toxins : Unravelling Oligomerization Pathways and Related Kinetics
Pore forming toxins are a class of proteins secreted from a wide variety of pathogens. These toxins are implicated in several diseases such as cholera, anthrax, tuberculosis and food poisoning. The toxin proteins are ... -
Modeling, Performance Analysis and Design of Wireless Networks for Embedded Sensing Applications
The general theme of this thesis is modeling, performance analysis, and design of wireless networks under standardized CSMA/CA MAC protocols. In particular, we consider two widely used MAC protocols, namely, IEEE 802.15.4, ... -
Crystal Structures of Native and AdoMet Bound rRNA Methyltransferase from Sinorhizobium meliloti : Structural Insights into rRNA Recognition. Evolutionary, Structural and Functional Studies on Nucleoid-Associated Proteins HU and IHF
DNA- and RNA-binding proteins play a central role in gene regulation, which includes transcriptional control, alternative splicing, post-translational and transcriptional modifications like methylation and acetylation among ... -
Motion Planning of Flexible One-dimensional Object and Hyper-redundant Robots
This thesis deals with motion planning of flexible one-dimensional objects and hyper-redundant serial robots moving in a plane or in three dimensional space. The flexible one-dimensional object is modeled as a continuous ... -
An Exploratory Framework for Cyclone Identification and Tracking
Analyzing depressions plays an important role in meteorology, especially in the study of cyclones. In particular, the study of the temporal evolution of cyclones requires a robust depression tracking framework. To cope ...