etd AT Indian Institute of Science: Recent submissions
Now showing items 221-240 of 6752
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Ankora: Notions of Multi-party Computation and Zero-knowledge Beyond Conventional Models
In the era of digitalization, data privacy and integrity are of utmost importance. Secure multiparty computation (MPC) and zero-knowledge (ZK) facilitate data privacy and integrity. MPC enables privacy-preserving collaborative ... -
Computational Studies of Heavier Main Group Elements: Control of Lewis Acidity of Bi and Sb by Charge and Ligand Design, and Structural Variations of [Fe(CO)4]2E2 and E2CH2 Isomers (E = C–Pb)
Traditional main group compounds demonstrate Lewis acidity due to the presence of vacant p- orbitals. Hydrides of lighter main group elements, such as NH3, function as Lewis bases. However, introducing highly electronegative ... -
Photodynamic Therapy and Cellular Imaging using Platinum(II) Conjugates of Boron-dipyrromethene and Curcumin
The present thesis portrays the rational design and successful synthesis of platinum(II) complexes for achieving photoactivated dual action anticancer properties. The research project centers on synthesis, comprehensive ... -
Structural characterization of Staphylococcal γ-hemolysin in the presence of a lipid environment using single particle cryo-EM
γ-Hemolysin (γ-HL) is a quintessential bicomponent β-pore forming toxin (β-PFT) belonging to the arsenal of “superbug” Staphylococcus aureus. Here, we performed negative staining-TEM and single particle cryo-EM-based ... -
Ultrafast Processes in Energetic Molecules
The thesis has been presented in two parts. In first part of the thesis, ultrafast relaxation dynamics of UV excitation induced chemistry via electronically excited states has been discussed. Taking one example from each ... -
PZT Based High-speed Electro-Optic Modulator- Material Development, Fabrication, and Photonic Device Characterization
Electro-optic (EO) modulator is a device that converts the electrical signal into an equivalent optical signal, which finds application in fields such as modulating the power of a laser beam, high-speed digital data ... -
The monopole-dimer model and eccentricities for Cartesian product of graphs
This thesis comprises two main parts. The details of the two parts are as follows: The first part of the thesis deals with the monopole-dimer model. The dimer (resp. monomer-dimer) model deals with weighted enumeration of ... -
Particles and Fields in Active Turbulence
I have extended various facets of modern turbulence theory to hydrodynamic models of dense bacterial suspensions, which show turbule= nt-like patterns, dubbed active turbulence. By using direct numerical simulations (DNSs) ... -
Interplay of Electrons and Phonons in 2D Materials
Since the seminal study by Cao et al. in 2018, that revealed the emergence of superconductivity and correlated insulating behaviour in twisted bilayer graphene (TBG), there has been a surge of exciting discoveries in moiré ... -
Holomorphic mappings and Kobayashi geometry of domains
In this thesis, we study certain aspects of the geometry of the Kobayashi (pseudo)distance and the Kobayashi (pseudo)metric for domains in $\mathbb{C}^n$. We focus on the following themes: on the interaction between Kobayashi ... -
Integrative multiscale modeling and simulations of biomolecules with experimentally testable predictions
This thesis delves into four separate research works related to Integrative multiscale modeling and simulations of biomolecules. The first work deals with the puzzling case of the Pleckstrin Homology Domain (PHD), which ... -
Unraveling the role of cellular phosphatases in lysosome function and storage diseases
Investigating the role of DUSP14 and Rab7A in endo-lysosomal trafficking in mammalian cells Eukaryotic cells maintain homeostasis and interact with their environment through intricate metabolic processes, including the ... -
Single and Multi-Agent Finite Horizon Reinforcement Learning Algorithms for Smart Grids
In this thesis, we study sequential decision-making under uncertainty in the context of smart grids using reinforcement learning. The underlying mathematical model for reinforcement learning algorithms are Markov Decision ... -
Crafting Complexity: Characterization and Tuning of Non-Hermitian Topological Phases
Quantum mechanics relies on self-adjoint or Hermitian operators, ensuring real eigenenergies and preserving probability via a unitary time evolution [1]. However, this applies strictly to closed systems. In open systems, ... -
Role of RTEL1 helicase in the regulation of homologous recombination during DNA replication
Homologous recombination (HR) plays an essential role in the repair of DNA double-strand breaks (DSBs), replication stress responses, and genome maintenance. Although the mechanism of HR has been extensively studied in the ... -
Analysis, Modelling, and Optimization of Gate-To-Gate Aircraft Operation for Enhanced Air Traffic Management
The global air passenger demand will surpass the 10 billion mark by the end of 2040. India itself is poised to become the third largest aviation market and traffic generator by 2033, with a forecast of over 950 million ... -
Sparse Input View Synthesis: 3D Representations and Reliable Priors
Novel view synthesis refers to the problem of synthesizing novel viewpoints of a scene given the images from a few viewpoints. This is a fundamental problem in computer vision and graphics, and enables a vast variety of ... -
Universal and Scalable Multi-Source Energy Harvesting Power Supply with Dynamic Load Adaptation
Autonomous powering of electronic systems in applications spanning biomedical, automation, transportation and space industries relies on harvesting energy from the abundant ambient sources such as vibration, thermal, solar, ... -
Unravelling Crosstalk in Two-component Signalling Systems and Its Role in Mycobacterium Species
A typical two-component signaling system (TCSs) is composed of two transcriptionally coupled proteins (cognate pair) where one is a signal-sensing histidine kinase (HK) and the other, an output-generating response regulator ... -
Emergence and Propagation of Aerodynamic Instabilities in Centrifugal Compressors with Vaned Diffusers: Effect of Solidity and Stagger
Centrifugal compressors are widely employed in turbochargers and small gas turbines due to their ability to achieve high compression per stage. These compressors consist of a rotating impeller and a static diffuser, which ...