etd AT Indian Institute of Science: Recent submissions
Now showing items 1-20 of 6865
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A Framework for Evaluating Hydrologic Risk of Dams and Dam-Break Floods Under Data-Sparse and Climate Change Scenarios
Design Flood Hydrograph (DFH) desirable for studies related to the planning, design, operation, and risk assessment of a dam is often derived using the Unit Hydrograph (UH) approach. It involves the convolution of UH of ... -
Barrier Coverage using UAVs and Camera Sensors
With advancements in camera sensor technology, camera sensor networks are increasingly utilized for border surveillance. UAVs equipped with downward-facing cameras also serve as effective sensors, and their features, ... -
Structural and Mechanistic Studies of Gaba Transporter Isoform 1
The plasma membrane neurotransmitter transporter, GAT1, is responsible for the clearance of inhibitory neurotransmitter γ-aminobutyric acid (GABA) from the synaptic cleft. Targeting GABA reuptake by inhibiting GAT1, hence ... -
Tuning Cellular Uptake of Small Molecules in Mammalian Cells by Substitution with Halogen and Chalcogen Atoms
Efficient cellular delivery of bioactive molecules is essential for the discovery and development of novel drugs. However, targeting intracellular proteins in the cytosol and other cellular components using small molecules ... -
Polarized Light Based Photoacoustics for Deep-Tissue Chiral Biomolecular Sensing
Sensing methodologies are indispensable for detecting and quantifying physical, chemical, and biological parameters with precision, especially for biomedical applications. These techniques enable early disease detection, ... -
Inflatable Aerodynamic Decelerators for Atmospheric Re-entry
Atmospheric re-entry is the most challenging part of human space flight. In the re-entry phase of flight, the crew module (or re-entry vehicle) is required to bring the onboard astronauts from orbital velocities, which ... -
Single and twin liquid jet injection in crossflow: Influence of Mach number and jet spacing
Supersonic air-breathing engine development towards hypersonic vehicles is challenging due to flow complexities arising from compressibility effects. In these engines, the incoming crossflow air enters the combustor at ... -
Numerical Studies on the Effect of Core Metal Type and Thickness on the Mechanical Behaviour of Fiber Metal Laminates
Fiber Metal Laminates are advanced materials that combine the properties of metals with Fiber Reinforced Plastics to attain enhanced mechanical performance. The desired mechanical properties can be achieved by hybridizing ... -
Turning an Antioxidant into a Prooxidant: Light-induced Mitochondrial Apoptosis in Mammalian Cells by an Ergothioneine-based Neutral Small Molecule
Mitochondria-targeted compounds gained significant interest due to their applications in fundamental research, diagnostics, and therapeutics. In this work, we present a detailed investigation of the ergothioneine-based ... -
Design and Fabrication of P3HT-Field Effect Transistors
The increasing demand for advanced sensing applications has highlighted the potential of hybrid systems combining silicon technology with organic field-effect transistors (OFETs). Silicon technology-based devices are ... -
In-situ Tribological Experiments to Study - The Effect of Contact Stresses on Raman Scattering
This thesis presents the design, development, and validation of novel instruments that enable in situ micro-Raman spectroscopic measurements at mechanically loaded interfaces: an indentation apparatus for static loading ... -
MOCVD of MoS2: Nucleation Density, Lateral Growth Rate, and Coverage Dependence on Growth Variables
Scaling towards increasing miniaturization, as per the so-called Moore’s law, has governed electronics technology by the CMOS route over the past decades. 2D materials atomically thin crystalline layers are emerging ... -
Sparse Input Novel View Synthesis of Dynamic Scenes
Novel view synthesis involves generating unseen perspectives of a scene based on videos captured from limited viewpoints. It is an interesting problem in computer graphics and computer vision, with many applications such ... -
Structure, thermodynamics and dielectric properties of water under nanoscale confinement and search for reversible phase change of methanol in astrochemical conditions
This thesis majorly explores the intricate structural, dynamical, and dielectric characteristics of monolayer water and other organic molecules under strong confinement and astrochemical condition. Water molecules ... -
Controller Synthesis Techniques for Infinite-State Reactive Systems
Reactive systems are ubiquitous, with various use cases ranging from controllers for cyber-physical systems to programs that run on multipurpose computers. A system is reactive if it continually behaves in a specific manner ... -
Physiological significance of tRNA sequences and modifications in regulation of the bacterial growth
Transfer RNA or tRNA is one of the vital components of translation machinery where it acts as an adaptor molecule to bring amino acid to the ribosome in response to the genetic code in mRNA. Its key role is to decode the ... -
Deciphering the mechanism behind the division of the Salmonella containing vacuole (SCV) and the immunomodulation strategy employed by Salmonella Typhimurium
The genus Salmonella represents flagellated, Gram-negative, rod-shaped anaerobic bacteria which is a leading cause of food-borne illness and causes enteric disease in a wide range of animals. In humans and several warm-blooded ... -
Inter-Numerology and Inter-Carrier Interference in Mixed-Numerology OFDM Systems
Mixed-numerology has been adopted in the orthogonal frequency division multiplexing (OFDM)-based physical layer of 5G new radio (NR) to serve diverse use cases and services. The subcarriers of different numerologies have ... -
The keeper of Chronicles - Investigating calcium carbonate archives using clumped thermometry
Calcium carbonates (CaCO3) are the most abundant mineral archive for reconstructing past climate owing to their tendency to register the environmental condition during their formation. From biogenically mediated carbonates ... -
Design, Optimization and Field Validation of Low Head Hydro Powered Turbine Pumps and Piston Pumps for driving stream flows in the range 40-120 l/s and 5-20 l/s respectively
This thesis focuses on developing optimized self-operating pumps using flows and head of perennial streams or rivers for decentralized irrigation and drinking water supply needs of local communities living by the river ...