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Structure and Dynamics of Interfacial Molecular Membranes
(2018-04-16)
This thesis describes the study on structure and dynamics of various kinds of molecular membranes in general. We have studied the morphological transition of colloidal as well as biologically relevant membranes and ...
Spiral-Wave Dynamics in Ionically Realistic Mathematical Models for Human Ventricular Tissue
(2018-04-18)
There is a growing consensus that life-threatening cardiac arrhythmias like ven- tricular tachycardia (VT) or ventricular fibrillation (VF) arise because of the formation of spiral waves of electrical activation in cardiac ...
Spiral- And Scroll- Wave Dynamics In Ironically And Anatomically Realistic Mathematical Models For Mammalian Ventricular Tissue
(2017-05-24)
Cardiac arrhythmias, such as ventricular tachycardia (VT) and ventricular fibrillation (VF), are among the leading causes of death in the industrialized world. There is growing consensus that these arrhythmias are associated ...
Optical Tweezers and Its use in Studying Red Blood Cells - Healthy and Infected
(2017-11-29)
The experiment discussed in the next chapter was to confirm the aforementioned bystander effect. In the first experiment we separated hosting and non-hosting mRBCs by the percol purification method and then measured the corner ...
X-Ray Crystallographic Studies Of Designed Peptides And Protected Omega Amino Acids : Structure, Conformation, Aggregation And Aromatic Interactions
(2009-05-18)
Peptides have assumed considerable importance in pharmaceutical industry and vaccine research. Understanding the structural features of these peptide molecules can be effective not only in mimicking natural proteins but ...
X-ray Crystallographic Characterization Of Designed Peptides Containing Heterochiral And Homochiral Diproline Segments And Database Analysis
(2010-12-30)
Understanding the relation between amino acid sequences and protein structures is one of the most important problems in modern molecular biology. However, due to the complexities in the protein structure, this task is ...
X-Ray Crystallograhic Studies On 2',5', Cyclic And Modified Nucleotides
(2007-09-05)
This thesis presents the crystal structures of 2', 5', cyclic and modified nucleosides / nucleotides. Chapter I gives a brief account of the structural studies on 2', 5' and modified nucleotides. It also presents a short, ...
Crystal Structure Of Abrus Precatorius Agglutinin-I (APA-I) : Insights Into The Reduced Toxicity Of APA-I In Relation To Abrin. Formation Of Ordered Nanotubes Through Self Assembly In The Crystal Structures Of Dipeptides Containing α. β-dehydrophenylalanine
(2009-07-22)
Ribosome Inactivating Proteins (RIPs) are protein or glycoprotein toxins that bring about the arrest of protein synthesis by directly interacting with and inactivating the ribosomes. Such toxins are in general, of plant ...
Contributions To Venominformatics : Sequence-Structure-Function Studies Of Toxins From Marine Cone Snails. Application Of Order-Statistics Filters For Detecting Membrane-Spanning Helices
(2009-07-21)
Venomous animals have evolved a vast array of peptide toxins for prey capture and defense. Nature has evolved the venoms into a huge library of active molecules with high selectivity and affinity, which could be explored ...
Development And Optimization Of A Microchip PCR System Using Fluorescence Detection
(2011-02-21)
Microfabricated thermal cyclers for nucleic acid amplification by using polymerase chain reaction (PCR) have been demonstrated by several groups over the last decade, with improved cycling speed and smaller volumes when ...