Browsing Physics (PHY) by Advisor "Sekar, K"
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Structural and functional studies on DNA synthesis and repair proteins
The work reported in this thesis includes structural and functional studies on thymidylate kinase and RecFOR pathway proteins from Thermus thermophilus HB8. In the first part, a study was performed on the thymidylate ... -
Structural Studies on Thymidylate Kinase : Evolution, Specificity and Catalysis
(2018-05-30)Thymidylate kinase (TMK) is a key enzyme for DNA synthesis. It occurs at the junction of the de novo and salvage pathways for the synthesis of deoxythymidine triphosphate (dTTP). Its inhibition affects cell viability, ...