Browsing Interdisciplinary mathematical sciences (IMS) by thesis submitted date"2024"
Now showing items 1-4 of 4
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Analysis, Modelling and Prediction of Protein-Protein Interfaces and Application to Biological Problems
Proteins play crucial roles in many biological processes like signalling, catalysis of metabolic processes, immune systems, and transporting molecules. To perform this wide range of functions, proteins interact with other ... -
A Digital Health framework for Personalized medicine: Development of a new algorithm for identifying concise actionable driver gene panels and application in Cancer and Rheumatoid Arthritis
Precision medicine, enabled by next-generation sequencing (NGS), has shown tremendous potential for use in a clinical setting for disease diagnosis and treatment. The biggest promise is to make treatments more precise and ... -
A divide-and-conquer distance geometry method to model protein structures from NMR spectroscopy
Nuclear Magnetic Resonance (NMR) spectroscopy provides insights into the dynamic behavior of proteins in solution, eliminating the need for crystallization. NMR experiments can spatially probe nuclei within 6 Angstroms of ... -
Modelling stimulus dependencies and temporal characteristics of Gamma Rhythm in Macaque Primary Visual Cortex
Gamma rhythm refers to oscillatory neural activity between 30 and 80 Hz, which represents the interaction between different classes of neurons. Gamma in the primary visual cortex (V1) is generated intrinsically while ...