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Droplet, Jets, and Leaky Surfaces
Surface structuring on a micro-nano scale, combined with a low surface energy coating, leads to anti-wetting properties. Such surfaces also exhibit other properties such as self-cleaning, antifouling, bacteriostatic, drag ...
Functional regulation of cytoplasmic dynein in vivo
In the crowded confines of the eukaryotic cell, where large cargo (> 100 nm) are diffusionaly constrained, intracellular transport by motor proteins plays a crucial role in the exchange of material between various compartments ...
Molecular determinants of self-assembly of the pore forming toxin Cytolysin A
Pore forming toxins (PFTs) belong to a class of bacterial exotoxins that disrupt the
biological membrane barrier by formation of nanopores. These toxins are central to
the virulence of pathogens such as S. pneumoniae, ...
Effect of Single Residue Change on Conformational Dynamics of Proteins and Their Function: A Molecular Dynamics Study
Proteins undergo conformational transitions and exhibit specific motion while performing their function. A single residue change (addition, deletion, or substitution) can sometimes influence the protein dynamics and disrupt ...
Caenorhabditis elegans-Bacteria interactions: Neuronal Regulation of Innate Immune Responses
The survival of an organism depends on its ability to sense threats and execute appropriate defense mechanisms. C. elegans is a soil-dwelling nematode that feeds on bacteria in rotting vegetation. The nematode has few ...
Engineering Graphene Oxide Surface Chemistry and Investigating Its Effect on The Physicochemical and Biological Properties
In the current study, systematic tuning of oxidation degree of GO has been explored and a two-step methodology for engineering GO surface chemistry was successfully developed. The investigation of the effects of oxidation ...
Insights into signalling and crosstalk in two-component signalling systems of Mycobacterium tuberculosis
Tuberculosis (TB), caused by the pathogen Mycobacterium tuberculosis (Mtb), has very recently reclaimed the position of the leading cause of deaths in humans from a single infection agent. This suggests a dire need to ...
Self-organisation of bacteria through swarming
Swarming is a unique example of social behaviour in bacteria. They represent the collective
effort of bacteria to translocate on moist substrates. The bacteria extract fluid from the
substrate through osmosis and produces ...
An Investigation of the Characteristics of Monsoon Low Pressure Systems in the Present Climate and their Sensitivity to Topography and Climate Change
Monsoon Low-Pressure Systems (LPS) are synoptic-scale tropical disturbances that periodically form over the Indian subcontinent during the summer monsoon season (June-September). Apart from being a lifeline to agriculture, ...
INTERPIN: identifying INtrinsic transcription TERminators, hairPINs in bacteria
The conversion of DNA to RNA through transcription is an important step in the life cycle of every organism. It ensures that the genetic information in DNA is converted through RNA into instructions/blueprints for the ...