Now showing items 1-10 of 181
An Integrated Systems Biology Approach to Study Drug Resistance in Mycobacteria
Emergence of drug resistance is a major problem in the treatment of many diseases including tuberculosis. To tackle the problem, it is essential to obtain a global perspective of the molecular mechanisms by which bacteria ...
Systems-Level Modelling And Simulation Of Mycobacterium Tuberculosis : Insights For Drug Discovery
Systems biology adopts an integrated approach to study and understand the function of biological systems, particularly, the response of such systems to perturbations, such as the inhibition of a reaction in a pathway, or ...
Structural Studies On Bovine Pancreatic Phospholipase A2 And Proteins Involved In Molybdenum Cofactor Biosynthesis
We have carried out structural studies on bovine pancreatic phospholipase A2 (BPLA2) and two proteins involved in molybdenum cofactor (Moco) biosynthesis pathway. In addition, molecular-dynamics simulations and other ...
Adaptive Grid Meta Scheduling - A QoS Perspective
A Computational Study Of Ion Crystals In Paul Traps
In this thesis we present a computational study of “ion crystals”, the interesting patterns in which ions arrange themselves in ion traps such as Paul and Penning traps. In ion crystals the ions are in equilibrium due to ...