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Total Synthesis of Bio-Active Macrolide Natural Products and Sulfinamide Based Ligands in Asymmetric Catalysis
(2018-07-18)
The thesis entitled “Total synthesis of bio-active macrolide natural products and sulphonamide based ligands in asymmetric catalysis” is divided into two chapters.
First chapter of the thesis describes the total synthesis ...
Palladium Catalyzed Refunctionalizations of Olefins : Novel Strategies for Construction of C-C, C-Hetero Bonds and Homogeneous Hydrogenation
(2018-07-18)
Chapter 1: Metal carbenoids in organic synthesis
The chapter describes the phenomena of metal carbenoid insertion reactions in two parts: Part A, and Part B. The study of N-tosylhydrazones as diazo precursor was commenced ...
Organocatalytic Cascade Cyclizations for the Enantioselective Synthesis of Spirooxindoles
(2018-06-18)
The thesis entitled “Organocatalytic Cascade Cyclizations for the Enantioselective Synthesis of Spirooxindoles” is divided into three chapters.
Chapter 1: Catalytic Enantioselective Michael Addition/Cyclization Cascade ...
The Role of Liposomal Hybrids and Gold Nanoparticles in the Efficacious Transport of Nucleic Acids and Small Molecular Drugs for Cancer Nanomedicine
(2018-07-23)
The thesis entitled “The Role of Liposomal Hybrids and Gold Nanoparticles in the Efficacious Transport of Nucleic Acids and Small Molecular Drugs for Cancer Nanomedicine” elucidates the preparation of various liposomal ...
Design and Synthesis of Peptidomimics Constrained in Helical and Sheet Conformations using a Novel Covalent Surrogate for the Peptide Main Chain Hydrogen Bond
(2018-07-20)
This thesis entitled “Design and Synthesis of Peptidomimics Constrained in Helical and Sheet Conformations Using a Novel Covalent Surrogate for the Peptide Main Chain Hydrogen Bond” is divided into six chapters.
Chapter ...
Alkynones Derived from Tartaric Acid : Efficient Building Blocks for the Synthesis of Macrolactone Natural Products
(2018-07-05)
The thesis describes the synthesis and application of various alkynones derived from the bis-Weinreb amide of tartaric acid in the total synthesis of macrolactone natural products. The thesis is divided into three sections. ...
Synthesis of Bivalent and Monovalent Sugar Ligands, their Interfacial and Solution Phase Lectin Bindng Studies
(2018-02-11)
Carbohydrate-protein interactions are responsible for several biological functions. While these interactions maintain high levels of specificities, the binding strength of individual carbohydrate-protein recognitions are ...
Controlling Stereochemistry at the Quaternary Center using Bifunctional (THIO)Urea Catalysis
(2018-06-05)
The thesis entitled “Controlling Stereochemistry at the Quaternary Center Using Bifunctional (Thio)urea Catalysis” is divided into five chapters.
Chapter 1: Catalytic Enantioselective Construction of Quaternary Stereocenters ...
Studies of Poly(Propyl Ether Imine) Dendrimers as Synthetic SiRNA Delivery Vectors with Relevance to Hepatitis C Virus Inhibition
(2018-06-05)
Dendrimers are synthetic macromolecules with branches-upon-branches structures, nanoscale dimensions and a high density of surface groups. Presence of multiple cationic sites in dendrimers permits their efficient nucleic ...
Novel Strategies for the Synthesis of Organo-Sulfur Compounds under Metal-Free Reaction Conditions
(2018-09-04)
The thesis titled “Novel Strategies for the Synthesis of Organo-Sulfur Compounds Under Metal-free Reaction conditions” is presented into three main sections.
Section A– deals with the synthesis of thiourea and thioamide.
Section ...