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Structural and Conformational Feature of RNA Duplexes
(2017-11-17)
In recent years, several interesting biological roles played by RNA have come to light. Apart from their known role in translation of genetic information from DNA to protein, they have been shown to act as enzymes as well ...
Sequence And Structural Determinants of Helices in Membrane Proteins
(2017-09-23)
Membrane proteins roughly constitute 30% of open reading frames in a genome and form 70% of current drug targets. They are classified as integral, peripheral membrane proteins and polypeptide toxins. α-helices and β -strands ...
Further Structural Studies on Jacalin and Genomics Search for Mycobacterial and Archeal Lectins
(2017-12-03)
This thesis consists of two parts. The first part is concerned with further structural and related studies of jacalin, one of the two lectins found in jack fruit seeds. The second part deals with the search of mycobacterial ...
Structural Studies on Mycobacterium Tuberculosis Peptidyl-tRNA Hydrolase and Ribosome Recycling Factor, Two Proteins Involved in Translation
(2017-11-27)
Protein synthesis is a process by which organisms manufacture their proteins that perform various cellular activities either alone or in combination with other similar or different molecules. In eubacteria, protein synthesis ...
Role of CG9650 in Neuronal Development And Function of Drosophila Melanogaster
(2017-10-05)
The nervous system is the most complex system in an organism. Functioning of the nervous system requires proper formation of neural cells, as well as accurate connectivity and signaling among them. While the major events ...
Exploring the Evolution of Cellobiose Utilization in Shigella Sonnei And the Conservation of ChbG Orthologs in Eukaryotes
(2017-10-11)
The chb operon constitutes the genes essential for utilization of chitooligosaccharides in Escherichia coli and related species. The six genes of the operon code for a transcriptional regulator (ChbR) of the operon, a ...
Role of Chemokine Receptor, CXCR4 Mediated Signaling in Cellular Senescence
(2017-10-05)
Cellular senescence has been proposed to be equivalent to organismal aging and is one of the outcomes of the cell fate decision process in response to DNA damage that occurs in cells. When a cell encounters DNA damage, the ...