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Design And Isolation Of Temperature Sensitive Mutants Of Gal4 In Yeast And Drosophila
Genomic and proteomic investigations have yielded, and continue to produce, a large amount of information about genes and their protein products. In contrast, the evidence bearing on physiological roles of specific proteins ...
Unravelling The Mechanisms Of Myofibrillogenesis And Human Myopathies Using Drosophila Mutants
Myofibrillogenesis is a complex process, which involves assembly of hundreds of structural proteins in a highly ordered manner to form the contractile structural unit of muscle, the sarcomere. Several myopathic conditions ...
Biochemical and Functional Studies on the Evolutionarily Conserved MPPED1/MPPED2 Protein Family
A large number of evolutionarily conserved genes have been identified by comparative genomics approaches. However, a considerable fraction of these genes lack functional characterization despite the availability of several ...